HPV

This study tests a combination of three drugs—bintrafusp alfa, PDS01ADC, and entinostat—in adults with advanced HPV-related cancers (like cervical, anal, or throat cancer) or certain colon cancers that haven't responded to standard treatment. The goal is to find a safe dose and s…

This study was designed for people with HPV-positive oropharyngeal cancer who still had signs of the virus in their blood after completing standard treatment. Researchers planned to give an immunotherapy drug called BALSTILIMAB to see if it could clear the virus and improve long-…

This study tests two experimental vaccines (HB-201 and HB-202) given with standard chemotherapy drugs (carboplatin and paclitaxel) to people with HPV16-positive oropharyngeal cancer. The goal is to see if this combination can shrink tumors enough to allow less intensive follow-up…

This study is testing a blood test that looks for HPV DNA in the blood of people treated for HPV-positive oropharyngeal cancer. The goal is to see if the test can find cancer recurrence earlier than standard follow-up methods. About 150 participants are being followed after treat…

This study looks at whether offering HPV self-sampling kits by mail, pharmacy, or clinic can make cervical cancer screening easier. One thousand women aged 25-65 in Quebec will try different ways to get and return the kit. The goal is to see which method works best and if women f…

This study tests if giving the HPV vaccine to children at age 9-10, instead of the usual 11-12, leads to more kids getting fully vaccinated before they are exposed to the virus. The goal is to prevent HPV-related cancers later in life. About 3,100 children in Colorado and Califor…

This study tests a community-driven campaign to increase HPV prevention among mother-daughter pairs in Nigeria. About 1,838 participants will take part in events and surveys. The goal is to get more girls vaccinated against HPV and more mothers to self-test for the virus, which c…

This study tests a school-based communication strategy to help more children aged 9-12 in South Africa get the HPV vaccine, which prevents cancers caused by HPV. The program involves health materials and vaccine provision in schools. Researchers will measure how many children sta…

This study looks at how well the HPV vaccine works in women living with HIV and whether self-collected HPV tests can improve cervical cancer screening. About 650 women will use a self-swab kit at home or in the clinic. Those with positive results will get follow-up exams. The goa…

This study looks at whether offering cervical cancer screening in the emergency department helps more people get tested. About 200 women and transgender/non-binary individuals with a cervix, aged 25-65, will be offered a self-sampling kit or clinic referral. Researchers will call…

This study looks at how the HPV vaccine (Gardasil-9) triggers a strong and lasting immune response. Researchers will track 17 healthy adults aged 18-45 who receive three doses of the vaccine. By analyzing blood, saliva, lymph nodes, and bone marrow over several years, they aim to…