HIGH GRADE GLIOMA (III OR IV)
Clinical trials for HIGH GRADE GLIOMA (III OR IV) explained in plain language.
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Experimental brain cancer drug NRG-103 enters first human tests
Disease control Recruiting nowThis early-stage trial tests an experimental drug called NRG-103 in about 24 adults with recurrent or progressive high-grade glioma, an aggressive brain cancer. The main goals are to find a safe dose and check for side effects, while also looking for early signs that the drug mig…
Matched conditions: HIGH GRADE GLIOMA (III OR IV)
Phase: PHASE1 • Sponsor: Neuregen Therapeutics Co., Ltd. • Aim: Disease control
Last updated Jul 19, 2026 00:00 UTC
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Can a cancer drug beat steroids for brain radiation injury?
Disease control Recruiting nowThis study compares bevacizumab (Avastin) to standard steroid treatment (dexamethasone) as the first therapy for people with brain radiation necrosis—a side effect of radiation therapy for brain tumors. About 408 participants with high-grade glioma or brain metastases will be ran…
Matched conditions: HIGH GRADE GLIOMA (III OR IV)
Phase: PHASE3 • Sponsor: The Netherlands Cancer Institute • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
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Glow-in-the-Dark drug could help surgeons spot brain cancer
Knowledge-focused Recruiting nowThis early-phase trial tests a special version of the immunotherapy drug nivolumab that has a fluorescent dye attached (nivo800). The dye makes the drug glow under near-infrared light, allowing researchers to see exactly where the drug goes in the tumor during surgery. About 38 a…
Matched conditions: HIGH GRADE GLIOMA (III OR IV)
Phase: EARLY_PHASE1 • Sponsor: Eben Rosenthal • Aim: Knowledge-focused
Last updated Jul 03, 2026 00:00 UTC
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Glowing probe aims to improve brain tumor diagnosis
Knowledge-focused Recruiting nowThis study is testing a new fiber optic probe that combines three technologies (fluorescence, Raman spectroscopy, and ultrasound) to help doctors see tumor tissue and blood vessels during brain biopsies. The probe will be tested on brain tumor tissue removed from 20 patients with…
Matched conditions: HIGH GRADE GLIOMA (III OR IV)
Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC