HIGH GRADE B-CELL LYMPHOMA WITH MYC AND BCL2 AND/OR BCL6 REARRANGEMENTS
Clinical trials for HIGH GRADE B-CELL LYMPHOMA WITH MYC AND BCL2 AND/OR BCL6 REARRANGEMENTS explained in plain language.
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Scientists test powerful new drug cocktail to fight Fast-Growing lymphomas
Disease control Recruiting nowThis early-stage study is testing the safety of adding one or two new targeted drugs to a standard chemotherapy regimen for people with untreated, fast-growing B-cell lymphomas. The goal is to see if this combination is tolerable for patients and to gather initial data on its eff…
Matched conditions: HIGH GRADE B-CELL LYMPHOMA WITH MYC AND BCL2 AND/OR BCL6 REARRANGEMENTS
Phase: PHASE1 • Sponsor: University of Washington • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New hope for Tough-to-Treat lymphomas: trial tests powerful drug combo
Disease control Recruiting nowThis study is testing whether adding a new immunotherapy drug called epcoritamab to a standard chemotherapy regimen (EPOCH-R) is safe and more effective for treating aggressive B-cell lymphomas. The trial will enroll about 18 adults who have not yet received treatment for their s…
Matched conditions: HIGH GRADE B-CELL LYMPHOMA WITH MYC AND BCL2 AND/OR BCL6 REARRANGEMENTS
Phase: PHASE2 • Sponsor: University of Washington • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New drug targets 'Undruggable' cancer driver in Tough-to-Treat lymphomas
Disease control Recruiting nowThis early-stage trial is testing a new drug called pidnarulex (CX-5461) in adults with aggressive, hard-to-treat B-cell lymphomas that have a specific genetic feature called MYC aberration. The main goals are to find the safest and most effective dose and to see if the drug can …
Matched conditions: HIGH GRADE B-CELL LYMPHOMA WITH MYC AND BCL2 AND/OR BCL6 REARRANGEMENTS
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Targeted attack on Tough-to-Treat blood cancer
Disease control Recruiting nowThis study is testing a new two-step treatment for people with a high-risk, aggressive type of lymphoma who haven't had treatment yet. First, patients receive a targeted drug that seeks out and kills cancer cells, followed by a standard chemotherapy regimen. The goal is to see if…
Matched conditions: HIGH GRADE B-CELL LYMPHOMA WITH MYC AND BCL2 AND/OR BCL6 REARRANGEMENTS
Phase: PHASE2 • Sponsor: Joseph Tuscano • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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Targeted drug combo offers hope for Tough-to-Treat leukemia
Disease control Recruiting nowThis study is testing a combination of a targeted cancer drug (inotuzumab ozogamicin), low-intensity chemotherapy, and an immunotherapy drug (blinatumomab) for adults with acute lymphoblastic leukemia (ALL). It focuses on older patients (60+) or younger patients who are too frail…
Matched conditions: HIGH GRADE B-CELL LYMPHOMA WITH MYC AND BCL2 AND/OR BCL6 REARRANGEMENTS
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Scientists test double punch against Tough-to-Treat blood cancer
Disease control Recruiting nowThis study is testing whether adding one of two new drugs (tazemetostat or zanubrutinib) to an existing two-drug therapy works better for controlling an aggressive type of blood cancer called large B-cell lymphoma. It is for adults whose cancer has returned or did not respond to …
Matched conditions: HIGH GRADE B-CELL LYMPHOMA WITH MYC AND BCL2 AND/OR BCL6 REARRANGEMENTS
Phase: PHASE2 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC