HEPATOBLASTOMA
Clinical trials for HEPATOBLASTOMA explained in plain language.
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Engineered immune cells take on childhood cancers in first human test
Disease control Recruiting nowThis early-phase study tests a personalized cell therapy for children and young adults up to age 21 with solid tumors that have returned or not responded to standard care. The therapy uses the patient's own immune T cells, which are genetically modified to recognize and attack a …
Matched conditions: HEPATOBLASTOMA
Phase: PHASE1 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Jun 16, 2026 12:53 UTC
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New hope for kids with tough liver cancer: combo therapy enters trial
Disease control Recruiting nowThis study tests a combination of three drugs (pucotenlimab, lenvatinib, and irinotecan) in children aged 2-18 with advanced hepatoblastoma that has not responded to prior treatment. The goal is to see if this approach can slow or stop cancer growth. Up to 24 children will receiv…
Matched conditions: HEPATOBLASTOMA
Phase: NA • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated Jun 15, 2026 19:04 UTC
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New hope for kids with rare liver cancer: smarter chemo on the horizon
Disease control Recruiting nowThis study tests a new combination of chemotherapy drugs for children and teens with hepatoblastoma, a rare liver cancer. The goal is to improve survival, especially for high-risk patients who currently have poor outcomes. About 100 participants under 18 will receive the treatmen…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE2 • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated Jun 12, 2026 12:08 UTC
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New hope for rare cancers: immunotherapy trial targets 40+ tumor types
Disease control Recruiting nowThis study tests the drug nivolumab in people with rare cancers that have spread and have not responded to standard treatments. It includes over 40 different rare tumor types, as long as the cancer cells have a specific marker called PD-L1. The goal is to see if nivolumab can shr…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE2 • Sponsor: Instituto do Cancer do Estado de São Paulo • Aim: Disease control
Last updated Jun 12, 2026 12:07 UTC
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Supercharged immune cells take on Hard-to-Treat cancers
Disease control Recruiting nowThis early-phase trial tests a new type of immunotherapy for adults with solid tumors that have a specific marker called GPC3. Researchers take a patient's own T cells and add three new genes to help them recognize and attack cancer cells more effectively, plus a safety switch to…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE1 • Sponsor: Baylor College of Medicine • Aim: Disease control
Last updated Jun 12, 2026 12:07 UTC
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New hope for kids with relapsed cancers: experimental drug combo enters trial
Disease control Recruiting nowThis early-phase study tests a four-drug combination (vorinostat plus three chemotherapy drugs) in children, teens, and young adults up to age 30 whose solid tumors or brain cancers have returned or not responded to standard treatment. The main goal is to find a safe dose and und…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE1 • Sponsor: New York Medical College • Aim: Disease control
Last updated Jun 11, 2026 12:09 UTC
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Engineered immune cells take on childhood cancers in new trial
Disease control Recruiting nowThis early-phase study tests a new type of immunotherapy for children and young adults with certain solid tumors that have come back or not responded to treatment. The therapy uses the patient's own immune cells, which are modified in a lab to better recognize and attack cancer c…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated Jun 10, 2026 13:26 UTC
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New hope for kids with liver cancer: Hearing-Saving drug added to chemo
Disease control Recruiting nowThis study tests a new treatment plan for children newly diagnosed with hepatoblastoma, a rare liver cancer. It includes a drug called sodium thiosulfate to help protect hearing during chemotherapy. The trial involves 330 children across multiple hospitals and aims to improve sur…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE3 • Sponsor: Shanghai Children's Medical Center • Aim: Disease control
Last updated Jun 09, 2026 12:09 UTC
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Scientists hunt for genetic clues in Kids' liver tumors
Knowledge-focused Recruiting nowThis study aims to uncover the genetic and molecular causes of liver cancer in children. Researchers will analyze DNA, gene activity, and other markers from up to 1,600 participants, including patients under 21 and their biological relatives. The goal is to better classify tumors…
Matched conditions: HEPATOBLASTOMA
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:56 UTC