HEPATIC ENCEPHALOPATHY

This study looks at whether adding L-carnitine, a natural substance, to standard care can improve outcomes for critically ill adults with liver disease in the ICU. About 58 participants with conditions like liver failure or severe infections will be enrolled. Researchers will tra…

This study compares a new procedure using a special stent (underdilated VCX-TIPS) with standard treatment (endoscopic banding plus beta-blockers) to prevent variceal rebleeding in people with cirrhosis. The new approach uses a smaller balloon to expand the stent, aiming to lower …

This study tests a new procedure that uses an endoscope (a thin tube with a camera) to guide coils and glue into abnormal blood vessels in the liver. The goal is to block these vessels and reduce severe confusion (hepatic encephalopathy) in people with liver cirrhosis. The trial …

This study tests whether a fecal microbiota transplant (FMT) from healthy donors can prevent severe confusion (hepatic encephalopathy) in 40 patients who still get episodes despite standard drugs after a liver shunt procedure (TIPS). Participants receive either FMT or a placebo, …

This study tests whether capsules containing gut microbes from healthy people can prevent future episodes of hepatic encephalopathy (a brain condition caused by liver problems) in 162 veterans with cirrhosis. Participants will take the capsules and be monitored for hospital visit…

This study looks at hepatic encephalopathy, a brain complication from liver cirrhosis that can cause memory loss and confusion. Researchers will follow over 700 liver cirrhosis patients and 120 healthy volunteers in China for up to 3 years. Participants use a simple phone app to …