HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS
Clinical trials for HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS explained in plain language.
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Promising new combo therapy targets rare immune disease in kids
Disease control OngoingThis study tests a personalized treatment plan using three drugs (ruxolitinib, dexamethasone, and etoposide) for children and young adults with a rare, life-threatening immune condition called HLH. The goal is to see if this combination can effectively control the disease while r…
Matched conditions: HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS
Phase: PHASE1, PHASE2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated May 17, 2026 04:23 UTC
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New hope for kids with 'Bubble Boy' disease: stem cell transplant study
Disease control OngoingThis study tests a stem cell transplant (bone marrow transplant) for people with severe immune system problems, like SCID (bubble boy disease) and Wiskott-Aldrich syndrome. The goal is to replace the faulty immune system with healthy donor cells. 57 participants will be followed …
Matched conditions: HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS
Phase: NA • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated May 17, 2026 04:14 UTC
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Milder stem cell transplant offers hope for kids with rare immune diseases
Disease control OngoingThis study tests a stem cell transplant for children and young adults up to age 28 with serious immune system disorders. The goal is to replace their faulty immune cells with healthy donor cells using a milder chemotherapy-like preparation to reduce side effects. The study tracks…
Matched conditions: HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated May 14, 2026 12:02 UTC