HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS
Clinical trials for HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS explained in plain language.
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Milder chemo may make stem cell transplants safer for Non-Cancer patients
Disease control Recruiting nowThis phase 2 trial tests a combination of three chemotherapy drugs (treosulfan, fludarabine, thiotepa) plus an immune-suppressing antibody before a donor stem cell transplant in up to 40 people under 50 with non-cancerous blood disorders. The goal is to see if this milder conditi…
Matched conditions: HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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New drug cocktail aims to tame deadly immune storm in lymphoma
Disease control Recruiting nowThis study tests a combination of two drugs, zanubrutinib and rituximab, for people with B-cell lymphoma who develop a severe immune overreaction called hemophagocytic lymphohistiocytosis (HLH). The trial will enroll 40 participants and aims to see how well the treatment controls…
Matched conditions: HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS
Phase: PHASE4 • Sponsor: The First Affiliated Hospital of Soochow University • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Massive study tracks hidden toll of rare immune diseases
Knowledge-focused Recruiting nowThis study follows 6,000 people with histiocytic disorders (like Langerhans cell histiocytosis) to understand long-term health problems, pain, mental health, and causes of death. Researchers compare participants to healthy controls to identify factors that lead to new health issu…
Matched conditions: HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS
Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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New HLH registry aims to unlock secrets of rare immune disease
Knowledge-focused Recruiting nowThis study is a registry that collects information from 200 people with hemophagocytic lymphohistiocytosis (HLH), a rare condition where the immune system becomes dangerously overactive. Researchers will track how quickly HLH is diagnosed, what treatments are used, and what compl…
Matched conditions: HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS
Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC