HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Clinical trials for HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM explained in plain language.
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New drug cocktail shows promise for rare cancers
Disease control OngoingThis phase 2 trial is testing whether a combination of two drugs, talazoparib and temozolomide, can shrink tumors in people with rare cancers that have spread. The study includes 14 participants with advanced rare solid tumors, such as pheochromocytoma or paraganglioma, who have …
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
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New hope for kids with rare cancers: targeted drug selpercatinib tested in phase 2 trial
Disease control OngoingThis phase 2 trial tests the drug selpercatinib in children and young adults (ages 1 to 21) with advanced cancers that have a specific genetic change called a RET alteration. The goal is to see if the drug can shrink tumors or stop them from growing. Only one participant has been…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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Targeted drug vismodegib tested against rare genetic cancers
Disease control OngoingThis phase 2 trial tests the drug vismodegib in 34 patients with advanced solid tumors, lymphoma, or multiple myeloma that have specific mutations in the SMO or PTCH1 genes. Vismodegib works by blocking a protein involved in cell growth. The main goal is to see if the drug can sh…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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New drug targets genetic weakness in Hard-to-Treat cancers
Disease control OngoingThis study tests a drug called copanlisib in people whose cancers have a specific genetic mutation (PIK3CA). The drug works by blocking a protein that helps cancer cells grow. Researchers want to see if it can shrink tumors or stop them from growing. About 35 adults with advanced…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New PET tracer could spot cancers that standard scans overlook
Diagnosis OngoingThis phase 1 trial is testing a new imaging tracer called 68Ga-FAPI-46 to see where it collects in normal and cancerous tissues. About 30 people with various solid tumors or blood cancers will receive the tracer and then undergo a PET/CT scan. The goal is to understand how the tr…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE1 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Diagnosis
Last updated Jul 04, 2026 00:00 UTC
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Poop pills may shield stem cell patients from deadly immune attack
Prevention OngoingThis study tests whether giving patients a transplant of healthy gut bacteria (from donated stool) can prevent severe graft-versus-host disease (GVHD) after a stem cell transplant. GVHD is a serious complication where donor immune cells attack the patient's body. The trial involv…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Prevention
Last updated Jul 22, 2026 00:00 UTC
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Firefighters' secret weapon against cancer? broccoli extract shows promise
Prevention OngoingThis study tests whether a daily broccoli seed and sprout extract (BSSE) can boost firefighters' natural ability to remove cancer-causing toxins from their bodies. Firefighters are often exposed to harmful chemicals like benzene, which increases their cancer risk. 72 firefighters…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Prevention
Last updated Jun 27, 2026 12:32 UTC
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Probiotic shows promise in preventing Life-Threatening transplant complication in kids
Prevention OngoingThis study tests whether a probiotic called Lactobacillus plantarum can prevent a serious complication called graft-versus-host disease (GvHD) in the gut of children receiving a donor stem cell transplant. About 173 children with blood cancers or other conditions are taking the p…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE3 • Sponsor: Children's Oncology Group • Aim: Prevention
Last updated Jun 27, 2026 07:54 UTC
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Magic mushroom therapy aims to ease cancer Patients' fear and sadness
Symptom relief OngoingThis study tests whether a group retreat using psilocybin (the active ingredient in magic mushrooms) can safely reduce anxiety and depression in people with incurable cancer. Participants will receive a pharmaceutical-grade psilocybin along with guided discussions to help them ga…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: University of Washington • Aim: Symptom relief
Last updated Aug 02, 2026 00:00 UTC
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Faith and mindfulness join forces to heal black cancer survivors
Symptom relief ENROLLING_BY_INVITATIONThis trial tests a mindfulness program that blends stress-reduction techniques with Christian principles to improve well-being in Black adult cancer survivors. Participants take part in a silent mindfulness retreat, focus groups, interviews, and questionnaires. The study measures…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: NA • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jul 23, 2026 00:00 UTC
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Virtual reality offers escape for bone marrow transplant patients
Symptom relief OngoingThis study tests whether using virtual reality (VR) can improve symptoms like pain, anxiety, and fatigue in patients receiving a bone marrow transplant. About 28 adults will be randomly assigned to either VR sessions or standard care during their hospital stay. The goal is to see…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: NA • Sponsor: Roswell Park Cancer Institute • Aim: Symptom relief
Last updated Jul 18, 2026 00:00 UTC
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Sniffing away sickness: essential oils tested for chemo nausea
Symptom relief TerminatedThis trial explores whether inhaling essential oils like peppermint, lavender, or ginger can help reduce nausea and anxiety in cancer patients receiving chemotherapy infusions. Current anti-nausea drugs often cause constipation and fatigue, so researchers are looking for gentler …
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: NA • Sponsor: City of Hope Medical Center • Aim: Symptom relief
Last updated Jul 15, 2026 00:00 UTC
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Antidepressant drug could fight cancer fatigue
Symptom relief OngoingThis phase 3 trial tests whether bupropion, a drug used for depression and smoking cessation, can reduce fatigue in 422 cancer survivors. Participants have stable disease or no evidence of cancer and report moderate to severe fatigue. They receive either bupropion or a placebo, a…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE3 • Sponsor: University of Rochester NCORP Research Base • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Sniffing lavender may ease biopsy pain and anxiety
Symptom relief TerminatedThis study tests whether inhaling lavender aromatherapy oil can reduce anxiety and pain for cancer patients undergoing a bone marrow biopsy. About 45 adults with cancer will be asked to use the oil during the procedure. The goal is to see if this simple, drug-free approach is som…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: NA • Sponsor: City of Hope Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Cancer patients with COVID-19: new study tracks their journey
Knowledge-focused OngoingThis study follows nearly 1,900 cancer patients who tested positive for COVID-19. Researchers collect blood samples, medical records, and images to see how the virus impacts their cancer treatment and overall health. The goal is to learn which factors make COVID-19 more severe in…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Aug 06, 2026 00:00 UTC
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New study tracks COVID-19 vaccine response in young cancer patients
Knowledge-focused OngoingThis study follows 549 children, teens, and young adults with cancer to see how their immune systems respond to COVID-19 vaccines. Researchers collect blood samples to measure protective antibodies. The goal is to learn how cancer and its treatment affect vaccine effectiveness, a…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: Children's Oncology Group • Aim: Knowledge-focused
Last updated Jul 18, 2026 00:00 UTC
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Cancer immunotherapy may throw patients off balance – literally
Knowledge-focused ENROLLING_BY_INVITATIONThis observational study at Mayo Clinic looks at how immunotherapy drugs affect balance and hearing in cancer patients. Researchers will test 50 adults before and during treatment to see if their vestibular (balance) system changes over a year. The goal is to better understand si…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Cannabis withdrawal in cancer patients: a hidden struggle during transplant?
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to find out how often cannabis withdrawal happens and how severe it is in patients with blood cancers who are hospitalized for a bone marrow transplant or CAR-T therapy. Researchers will track symptoms like mood changes and physical discomfort using a standard que…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Prison health survey aims to boost cancer screening for incarcerated women
Knowledge-focused ENROLLING_BY_INVITATIONThis study surveys 1,200 incarcerated women at a Florida prison to understand their cancer screening history, awareness, and barriers. The goal is to use this information to create a digital education module on cancer screening for prisons. No treatment or intervention is given; …
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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New study aims to improve cancer care for seniors
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at whether training and support can help cancer clinics give special check-ups (called geriatric assessments) to patients aged 65 and older who are starting a new cancer treatment. These check-ups help find and address health issues, support needs, and daily life…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Light therapy under the microscope: can it soothe mouth sores after transplant?
Knowledge-focused OngoingThis study looks at how photobiomodulation (a type of light therapy) affects mouth sores and other oral symptoms in patients receiving a stem cell transplant. Researchers will track pain, taste changes, and dry mouth in about 6 patients. The goal is to gather information to impro…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC