HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Clinical trials for HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM explained in plain language.
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New drug combo shows promise for rare, Hard-to-Treat cancers
Disease control OngoingThis study tests whether a combination of two drugs, talazoparib and temozolomide, can shrink advanced rare cancers or stop them from growing. The trial includes 14 adults with rare solid tumors that have not responded to standard treatments. Talazoparib blocks a protein that hel…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 17, 2026 04:16 UTC
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New targeted drug shows promise for kids with rare RET-Driven cancers
Disease control OngoingThis study tests a drug called selpercatinib in children and young adults (ages 1 to 21) whose cancers have a specific genetic change called a RET alteration. The goal is to see if the drug can shrink tumors or stop them from growing. The trial is for patients with advanced solid…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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New drug targets genetic weakness in Hard-to-Treat cancers
Disease control OngoingThis study tests a drug called copanlisib in people whose cancers have a specific genetic mutation (PIK3CA). The drug blocks a protein that helps cancer cells grow. Researchers want to see if it can shrink tumors or stop them from growing. About 35 adults with advanced or hard-to…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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New hope for hard-to-treat cancers with rare gene mutations
Disease control OngoingThis study tests a drug called vismodegib in people with advanced or treatment-resistant cancers (solid tumors, lymphoma, or multiple myeloma) that have specific changes in the SMO or PTCH1 genes. The drug blocks a protein that helps cancer grow. The goal is to see if the drug ca…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 12, 2026 13:43 UTC
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Firefighters fight cancer with broccoli: new study tests detox power
Disease control OngoingThis study tests whether a daily supplement made from broccoli seeds and sprouts can help firefighters remove harmful chemicals from their bodies. Firefighters are often exposed to cancer-causing substances like benzene from smoke and fires. The trial involves 72 firefighters who…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 08, 2026 12:03 UTC
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Poop pills may shield stem cell patients from deadly immune attack
Prevention OngoingThis study tests whether giving patients a fecal transplant (processed donor stool in capsules) after a stem cell transplant can prevent severe graft-versus-host disease (GVHD), a serious complication where donor cells attack the patient's body. The trial involves 138 adults who …
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Prevention
Last updated May 17, 2026 04:15 UTC
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Probiotic shows promise in preventing deadly Graft-Versus-Host disease in kids
Prevention OngoingThis study tests whether a probiotic called Lactobacillus plantarum can prevent acute graft-versus-host disease (GvHD) in the gut of children receiving donor stem cell transplants. About 173 children with blood cancers or other conditions will take the probiotic or a placebo. The…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE3 • Sponsor: Children's Oncology Group • Aim: Prevention
Last updated May 15, 2026 11:54 UTC
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Can an antidepressant beat cancer fatigue? new trial investigates
Symptom relief OngoingThis phase 3 trial tests whether bupropion, a drug used for depression and smoking cessation, can reduce fatigue in cancer survivors. About 422 adults who have completed cancer treatment and still suffer from moderate to severe fatigue will take bupropion or a placebo. The study …
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE3 • Sponsor: University of Rochester NCORP Research Base • Aim: Symptom relief
Last updated May 17, 2026 04:17 UTC
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Sniffing lavender may take the edge off painful cancer biopsies
Symptom relief TerminatedThis study looks at whether breathing in lavender aromatherapy oil can help cancer patients feel less pain and anxiety during a bone marrow biopsy. About 45 adults with cancer who are nervous about the procedure will try the oil or a placebo. The goal is to find a simple, drug-fr…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: NA • Sponsor: City of Hope Medical Center • Aim: Symptom relief
Last updated May 17, 2026 04:17 UTC
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Light therapy may soothe mouth pain for transplant patients
Symptom relief OngoingThis study looks at whether a special light treatment (photobiomodulation) can help reduce mouth sores, pain, taste changes, and dry mouth in patients receiving a stem cell transplant. Six adult patients with blood or solid tumor cancers are being studied. The goal is to see if t…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: City of Hope Medical Center • Aim: Symptom relief
Last updated May 13, 2026 15:59 UTC
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Cancer patients with COVID-19: new study tracks outcomes
Knowledge-focused OngoingThis study follows nearly 1,900 cancer patients who tested positive for COVID-19 to learn how the virus impacts their health and cancer treatment. Researchers collect blood samples, medical records, and images to identify factors linked to severe COVID-19 and changes in cancer th…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated May 17, 2026 04:33 UTC
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Cancer treatment may throw you off balance – new study investigates
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at how immunotherapy drugs affect balance and hearing in people with cancer. Researchers will test 50 patients before and during their standard immunotherapy treatment. The goal is to understand if these treatments cause dizziness or hearing changes, helping doct…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 17, 2026 04:14 UTC
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Prison health study aims to boost cancer screening for incarcerated women
Knowledge-focused ENROLLING_BY_INVITATIONThis study surveys about 1,200 women at a Florida prison to understand their cancer screening history, risk factors, and barriers to care. The information will be used to create a digital education module on screenable cancers and guidelines. The goal is to improve health literac…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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Cancer Kids' COVID shot response under microscope
Knowledge-focused OngoingThis study tracks how the immune systems of 549 children, teens, and young adults with cancer respond to COVID-19 vaccination. Cancer and its treatments can weaken immunity, so researchers want to see if factors like vaccine type, timing, and booster doses affect protection. The …
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: Children's Oncology Group • Aim: Knowledge-focused
Last updated May 11, 2026 20:48 UTC
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Can training cancer staff improve care for older patients?
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at whether training and supporting cancer clinic staff can help them give a special health check-up (called a geriatric assessment) to adults aged 65 and older before they start a new cancer therapy. The check-up covers physical health, social support, and daily …
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated May 07, 2026 18:41 UTC