HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Clinical trials for HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM explained in plain language.
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New drug duo targets Hard-to-Treat rare cancers
Disease control OngoingThis study is testing whether a combination of two oral drugs, talazoparib and temozolomide, can shrink advanced rare cancers that have spread and for which standard treatments have stopped working. The trial aims to see if this drug pair can stop tumor growth by damaging cancer …
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Targeted drug trial offers hope for Tough-to-Treat cancers with rare mutations
Disease control OngoingThis study is testing whether the drug vismodegib can help control advanced cancers that have specific genetic mutations and have stopped responding to standard treatments. The trial includes 35 adults with solid tumors, lymphoma, or multiple myeloma that have spread or are resis…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New drug targets Cancer's genetic weakness in Hard-to-Treat cases
Disease control OngoingThis study is testing whether a drug called copanlisib can shrink or stop the growth of advanced cancers that have a specific genetic change called a PIK3CA mutation. The drug works by blocking a protein that cancer cells need to grow. The trial includes 35 adults with various ad…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Targeted drug trial offers hope for kids with Hard-to-Treat cancers
Disease control OngoingThis study is testing a targeted drug called selpercatinib in children and young adults with advanced or returning cancers that have specific changes in a gene called RET. The goal is to see if the drug can shrink tumors and control the cancer's growth. Participants take the drug…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Poop pills tested to stop deadly transplant complication
Disease control OngoingThis study is testing whether taking capsules containing processed, healthy stool (fecal microbiota) can prevent severe graft-versus-host disease (GVHD) in adults who have received a bone marrow transplant. GVHD is a serious and common complication where the donor's immune cells …
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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Friendly bacteria vs. transplant danger: can a probiotic shield kids?
Prevention OngoingThis study is testing whether a specific probiotic (Lactobacillus plantarum) can prevent a serious complication called acute graft-versus-host disease (GvHD) in children, teens, and young adults getting a stem cell transplant from a donor for cancers like leukemia or lymphoma. Ab…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE3 • Sponsor: Children's Oncology Group • Aim: Prevention
Last updated Mar 30, 2026 14:28 UTC
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Blood test could guide drug to stop transplant rejection
Prevention TerminatedThis study is testing if a drug called ruxolitinib can prevent a serious complication called chronic graft-versus-host disease (GVHD) in patients who have received a bone marrow transplant for blood cancer. Researchers will first use a blood test to identify patients at high risk…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Prevention
Last updated Mar 23, 2026 15:18 UTC
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Broccoli pill trial aims to shield firefighters from cancer
Prevention OngoingThis study is testing whether a daily broccoli seed and sprout extract can boost the body's natural ability to clear out cancer-causing chemicals that firefighters breathe in during their work. It involves 66 active, non-smoking firefighters who will take either the broccoli extr…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Prevention
Last updated Mar 02, 2026 15:21 UTC
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Can a common antidepressant ease the exhaustion of cancer survivors?
Symptom relief OngoingThis study is testing whether the drug bupropion can help reduce severe, long-lasting fatigue in people who have finished their main cancer treatments. Researchers are comparing the drug against a placebo (a dummy pill) in over 400 cancer survivors. The goal is to see if this med…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: PHASE3 • Sponsor: University of Rochester NCORP Research Base • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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Shining a light on cancer treatment pain
Symptom relief OngoingThis study looks at whether a special light therapy can help reduce painful mouth sores and other oral problems in cancer patients receiving stem cell transplants. Researchers will observe 6 adult patients and their nurses to see how well the therapy works at controlling symptoms…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: City of Hope Medical Center • Aim: Symptom relief
Last updated Mar 25, 2026 14:08 UTC
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Can a simple scent ease the fear of cancer biopsies?
Symptom relief TerminatedThis study is testing whether smelling lavender or similar scents can help reduce pain and anxiety for cancer patients during bone marrow biopsy procedures. Researchers want to see if this simple, drug-free approach can make these uncomfortable tests easier to tolerate. The trial…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: NA • Sponsor: City of Hope Medical Center • Aim: Symptom relief
Last updated Mar 16, 2026 15:25 UTC
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Mayo clinic launches major survey to tackle cancer screening gaps in prisons
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to understand cancer screening awareness and barriers among incarcerated women. Researchers will survey 1,200 women at a Florida prison to learn about their knowledge, screening history, and challenges. The information will be used to create a digital education pr…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Major cancer study tracks COVID's impact on treatment and survival
Knowledge-focused OngoingThis study is observing people who have cancer and also get COVID-19. Researchers are collecting blood samples and health information from nearly 1,900 participants over two years. The goal is to understand how having cancer changes the course of COVID-19, and how getting COVID-1…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Do cancer immunotherapies make patients dizzy? mayo clinic investigates
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to understand if immunotherapy treatments for cancer affect a patient's balance and hearing. Researchers will follow 50 adults who are starting specific immunotherapies as part of their standard cancer care. They will compare balance and hearing tests done before …
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:27 UTC
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Scientists track how young cancer patients respond to COVID shots
Knowledge-focused OngoingThis study aims to understand how well the COVID-19 vaccine works in children, teens, and young adults who have cancer. Researchers are observing about 550 participants who are getting vaccinated during or after their cancer treatment. They will check blood samples over two years…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Sponsor: Children's Oncology Group • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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New training aims to help cancer clinics better care for older patients
Knowledge-focused ENROLLING_BY_INVITATIONThis study is testing whether providing training and support to cancer clinic staff helps them deliver a special health check-up for older adults starting new cancer treatments. The check-up looks at a patient's overall physical health, support network, and daily life impact, not…
Matched conditions: HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:14 UTC