New drug targets genetic weakness in Hard-to-Treat cancers

NCT ID NCT05490771

First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 26 times

Summary

This study tests a drug called copanlisib in people whose advanced cancer has a specific genetic change (PIK3CA mutation). The drug blocks a protein that helps cancer cells grow. Researchers want to see if it can shrink tumors or stop them from growing. About 35 adults with various advanced or hard-to-treat cancers are taking part.

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Contacts and locations

Locations

  • ECOG-ACRIN Cancer Research Group

    Philadelphia, Pennsylvania, 19103, United States

Conditions

Explore the condition pages connected to this study.