HEMATOLOGICAL MALIGNANCIES
Clinical trials for HEMATOLOGICAL MALIGNANCIES explained in plain language.
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New drug after transplant shows promise for blood cancer patients
Disease control CompletedThis study tested whether giving a drug called cyclophosphamide after a stem cell transplant could help the donor cells settle in better and reduce serious side effects like graft-versus-host disease (GVHD). It involved 78 people with blood cancers who received stem cells from a …
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated May 17, 2026 05:08 UTC
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Expanded cord blood cells show promise in speeding recovery for blood cancer patients
Disease control CompletedThis study tested a new cord blood product called NiCord, which is grown in a lab to have more stem cells, against standard cord blood transplants for people with blood cancers like leukemia and lymphoma. The goal was to see if NiCord helps the body rebuild its blood and immune s…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: PHASE3 • Sponsor: Gamida Cell ltd • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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New drug combo shows promise for Hard-to-Treat blood cancers
Disease control CompletedThis study tested a new drug combination (MK-7684A) in 192 people with blood cancers like lymphoma and multiple myeloma that had returned or stopped responding to prior treatments. The goal was to see if the drug is safe and can shrink tumors or control the disease. Participants …
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: PHASE2 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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New Two-Step transplant shows promise for tough blood cancers
Disease control CompletedThis study tested a two-step stem cell transplant using a drug called cyclophosphamide to lower the risk of graft-versus-host disease (GVHD) in people with high-risk blood cancers like leukemia and lymphoma. 47 patients received a transplant from a matched sibling donor. The goal…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated May 04, 2026 16:20 UTC
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PET scans tested to guide therapy for hidden fungal infection
Knowledge-focused CompletedThis study looked at whether a special scan (PET scan) can help doctors decide the best treatment for a rare fungal infection of the liver and spleen in people with blood cancer. One hundred adults who had recently recovered from low white blood cell counts and had suspicious spo…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated May 11, 2026 20:50 UTC
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Gene type may affect how cancer drug works in patients
Knowledge-focused CompletedThis early-phase study looked at how the cancer drug belinostat is processed in the body based on a person's UGT1A1 gene type. Seventeen adults with advanced solid tumors or blood cancers that had come back or stopped responding to treatment took part. The goal was to measure dru…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: PHASE1 • Sponsor: Acrotech Biopharma Inc. • Aim: Knowledge-focused
Last updated May 11, 2026 20:38 UTC