HEMATOLOGIC DISEASES

This study tested a one-time treatment for people with severe beta-thalassemia, a genetic blood disorder that requires regular blood transfusions to survive. Doctors used CRISPR gene-editing technology to modify a patient's own blood stem cells, then gave them back as a transplan…

This early-phase study tested a new type of cell therapy called RD13-02 in a small group of patients with aggressive blood cancers that had returned or not responded to standard treatments. The main goals were to check if the treatment was safe and to see how the modified immune …

This study tested whether adding a new drug called asciminib to the standard treatment imatinib could help patients with chronic myeloid leukemia (CML) achieve a deeper level of disease control. It involved 104 adults whose CML was not fully controlled by imatinib alone. Particip…

This study tested whether a special breathing technique, called cardiac coherence training, combined with a tailored exercise program could improve the quality of life for adults who had been treated for blood cancers like leukemia or lymphoma. 80 participants were randomly assig…

This study looked at lung scan patterns in 148 adults with blood cancers who developed lung problems. Researchers analyzed CT scans to identify common patterns of lung damage that occur in these patients. The goal is to help doctors better recognize and understand these complicat…

This completed study aimed to see if certain blood measurements could help predict how newly diagnosed multiple myeloma patients might fare. Researchers followed 48 patients for one year after diagnosis, checking their blood thickness and protein ratios. The goal was to find conn…

This early-stage study tested the safety and how the body processes multiple doses of a new drug called RLYB116. It involved 16 healthy adults to see how well they tolerated the drug and to measure its levels and effects in the blood. The goal was to gather initial safety data be…