HEMATOLOGIC DISEASES

This study tested a one-time treatment using CRISPR gene editing to fix a patient's own blood stem cells, aiming to help people with severe beta-thalassemia stop needing regular blood transfusions. 59 participants received the modified cells after a short course of chemotherapy. …

This early-phase study tested a new treatment called RD13-02, which uses a patient's own immune cells modified to attack cancer cells with a specific marker (CD7). It involved just 2 people with blood cancers like T-cell acute lymphoblastic leukemia that had come back or not resp…

This study tested whether adding the experimental drug asciminib to the standard treatment imatinib helps people with chronic myeloid leukemia (CML) achieve a deeper molecular response (very low cancer levels). It included 104 adults who had been on imatinib for at least a year b…

This study tested a program to help stem cell transplant survivors who have sexual problems. About 230 adults who had a transplant for blood cancer took part. The program aimed to improve sexual function, quality of life, and mood.

This study tested whether adding heart rate variability biofeedback (a technique to help control your heartbeat rhythm) to regular physical activity could improve quality of life in people who finished treatment for blood cancers. 80 adults in remission took part. The goal was to…

This study looked at whether a mobile phone app called Roadmap 2.0 could improve the quality of life for caregivers and patients going through a stem cell transplant. 372 caregivers and patients took part. The app was designed to provide support and track health, with the goal of…

This study examined 148 adults with blood diseases to identify lung complications using radiological imaging. The goal was to better understand the types and patterns of lung involvement, which can be caused by the disease itself, treatments, or other health issues. The findings …

This study checked if three simple blood measurements—blood thickness, albumin/fibrinogen ratio, and red cell distribution width—can help predict how newly diagnosed multiple myeloma patients will do over one year. Researchers followed 48 patients for a year after diagnosis, comp…

This study looked at cancer patients with diarrhea who tested positive for C. diff bacteria but negative for the toxin that usually causes illness. Half received an antibiotic (vancomycin) and half received a placebo for 14 days. The goal was to see how the treatment affected bac…

This early-stage study tested the safety and how the body handles a new drug called RLYB116 in 16 healthy adults aged 18 to 55. Participants received multiple doses, and researchers monitored side effects, drug levels, and immune reactions. The goal was to gather safety informati…

This study looked at whether it is safe to lower the platelet count that triggers a transfusion before placing a central venous catheter (a special IV line) in patients with blood disorders. Researchers compared a new, lower threshold (10,000 platelets per cubic millimeter) to th…