HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Clinical trials for HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF) explained in plain language.
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Heart failure drug shows promise for better blood flow and Well-Being
Symptom relief CompletedThis study looked at whether the drug vericiguat can improve blood vessel function, reduce inflammation, and help people with heart failure feel better. Twenty-six adults with heart failure and reduced pumping ability took part. Researchers measured changes in blood vessel health…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Phase: PHASE4 • Sponsor: Josef Stehlik • Aim: Symptom relief
Last updated May 14, 2026 12:03 UTC
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New heart failure drug passes first safety check in small study
Symptom relief CompletedThis early-stage study tested a new drug called XXB750 in 27 adults with heart failure (a weakened heart). The main goal was to see if the drug is safe and what side effects it might cause. Participants received either the drug or a placebo, and researchers monitored their health…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Phase: PHASE1 • Sponsor: Novartis Pharmaceuticals • Aim: Symptom relief
Last updated May 12, 2026 13:41 UTC
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Heart failure risk prediction gets a boost from blood and imaging combo
Knowledge-focused CompletedThis study looked at medical records of 4,000 heart failure patients to see if combining routine blood tests (like NT-proBNP) with heart scan results (like fat density around the heart) could better predict who might die within a year. The goal is to improve personalized risk ass…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Sponsor: Xinjiang Medical University • Aim: Knowledge-focused
Last updated May 17, 2026 04:11 UTC
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Heart failure rhythm clues found in blood metabolites
Knowledge-focused CompletedThis completed study looked at 60 adults with heart failure and a history of dangerous heart rhythms (ventricular tachycardia). Researchers compared blood-based metabolic profiles between those whose heart failure was caused by blocked arteries (ischemic) versus other causes (non…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Sponsor: Muhammed Heja Geçit • Aim: Knowledge-focused
Last updated May 17, 2026 04:10 UTC