HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Clinical trials for HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF) explained in plain language.
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Women's heart failure: aggressive drug strategy put to the test
Disease control Not yet recruitingThis study tests whether quickly starting and increasing heart failure medications in women after a hospital stay can lower the risk of death or another hospital visit within a year. About 360 women from 13 hospitals in Italy will be randomly assigned to either an intensive medic…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Phase: PHASE4 • Sponsor: IRCCS Policlinico S. Donato • Aim: Disease control
Last updated May 17, 2026 03:57 UTC
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New catheter treatment for heart failure put to the test
Disease control Not yet recruitingThis early-stage trial tests a new procedure that uses a catheter to treat a nerve in the chest, which may help people with heart failure with reduced ejection fraction. Up to 50 patients will be randomly assigned to receive the real treatment or a sham procedure, and neither the…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Phase: NA • Sponsor: Axon Therapies, Inc. • Aim: Disease control
Last updated May 15, 2026 12:07 UTC
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New pill could help failing hearts pump better
Disease control Not yet recruitingThis study tests an experimental oral drug called AC01 in 400 people with chronic advanced heart failure and a weak heart pump. Participants will take either a low dose, high dose, or placebo daily for 12 weeks. The goal is to see if AC01 safely improves heart function, measured …
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Phase: PHASE2 • Sponsor: AnaCardio AB • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Heart device aims to boost energy in failing hearts
Disease control Not yet recruitingThis study tests a small device placed in the heart to lower pressure and improve energy use in people with advanced heart failure. Researchers will use heart scans and exercise tests to see if the device helps the heart work better. The study plans to enroll 15 adults with sever…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Phase: NA • Sponsor: Heinrich-Heine University, Duesseldorf • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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New study aims to predict heart failure outcomes using Body's inner clues
Knowledge-focused Not yet recruitingThis study will follow 400 people with chronic heart failure and 200 healthy volunteers for one year. Researchers will collect blood, stool, and imaging data to find patterns that predict who might need to go back to the hospital or die from heart failure. The goal is to build a …
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Sponsor: Xinjiang Medical University • Aim: Knowledge-focused
Last updated May 17, 2026 04:09 UTC