Could zapping a nerve ease heart failure? new trial tests it
NCT ID NCT07403058
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage trial tests whether a catheter-based procedure that zaps a nerve near the spine can safely help people with heart failure with reduced ejection fraction. Up to 50 patients will be randomly assigned to get the real treatment or a sham procedure, and neither they nor their heart doctor will know which they received. The study focuses on safety and early signs of benefit, not long-term effectiveness.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
catheter-based nerve ablation (Satera Ablation System)
What this could lead to
If it works, this could offer a new way to manage heart failure symptoms without drugs or surgery.
What could go wrong
This is a very early, small feasibility trial. The procedure may not work better than a sham, and there are risks like pain or blood vessel damage.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hospital Clínico Universitario de Valencia-INCLIVA
Valencia, Spain
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King's College London
London, United Kingdom
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Leeds General Infirmary
Leeds, United Kingdom
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Motol and Homolka University Hospital
Prague, Czechia
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Uniwersytecki Szpital Kliniczny im. Jana Mikulicza Radeckiego we Wrocławiu
Wroclaw, Poland
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Vithas Valencia Turia
Valencia, Spain