HEART DISEASES

This study aims to see if a new type of heart stent called Freesolve is as safe and effective as a standard metal stent (Xience). Freesolve is made of magnesium and is designed to dissolve in the artery over time. The study will involve about 1,859 adults with clogged heart arter…

This study is testing a new program called ONLOOP that reminds adult survivors of childhood cancer in Ontario to get important health screenings. Many survivors are at higher risk for heart problems, breast cancer, or colon cancer due to their past cancer treatments, but often mi…

This study aims to find out which of two common surgical techniques is better for closing the breastbone after open-heart surgery in patients at high risk for healing problems. Researchers will compare rigid metal plates to traditional wire loops in 250 patients. The main goals a…

This study is testing whether adding special breathing exercises to standard cardiac rehab helps patients recover better from heart conditions. Researchers will enroll 80 adults who have had heart attacks, surgeries, or other serious heart problems. They'll measure if these exerc…

This early study is testing a small, self-expanding device called the A-FLUX Reducer. It is implanted in a vein near the heart to see if it can safely reduce chest pain in people with coronary microvascular dysfunction, a condition where tiny heart vessels don't work properly. Th…

This study aims to learn how a specific inherited form of heart muscle disease (dilated cardiomyopathy) progresses over time in adults who have a harmful change in their BAG3 gene. Researchers will follow about 30 patients to document their symptoms, heart function, and quality o…