HEALTHY VOLUNTEER

This early-stage trial is testing a new drug called MD-18 in healthy adults who are overweight or obese. The main goal is to check if the drug is safe and how the body processes it. About 54 participants will receive either MD-18 or a placebo by injection. The study is currently …

This study is testing a smartphone app called QbMobile that measures attention, impulsivity, activity, and movement patterns. Researchers want to see if it can provide objective data to help diagnose ADHD in people aged 6 to 60. The study includes 700 participants with and withou…

This study tests a new PET heart scan that uses 100 times less radiation than current methods. Researchers will scan 200 adults with known or suspected heart artery disease to see if the ultra-low dose still produces clear images. The goal is to make heart imaging safer while kee…

This Phase 1 study will give a single dose of ABBV-932 (with a tiny radioactive marker) to 8 healthy men. The goal is to measure how the drug moves through the body, how long it stays, and how it is eliminated. Researchers will also check for any side effects. This is a safety an…

This is a first-in-human study to see if ABBV-722 is safe and how the body handles it. About 95 healthy adults will receive either the drug or a placebo. The goal is to check for side effects and measure drug levels in the blood, not to treat any disease.

This study screens up to 10,000 people with blood disorders or healthy volunteers to see if they can safely join other active research studies at the National Heart, Lung, and Blood Institute. Participants undergo clinical, imaging, and lab tests. If no suitable study is availabl…

This study looks at how a new drug called ABBV-722 affects birth control pills in 16 healthy volunteers. Researchers want to see if ABBV-722 changes the levels of the hormones in the pill. This helps doctors know if the pill still works well when taken with ABBV-722.

This early-phase trial is testing the safety and tolerability of a new drug called D-2570 in 36 healthy volunteers. Participants receive either the drug or a placebo, and researchers monitor side effects and how the drug moves through the body. Since this is a Phase 1 study in he…

This early-phase study tests whether a new type of PET scan can measure inflammation in the brains of people with Parkinson's disease. Researchers will compare scans from 11 participants (both with Parkinson's and healthy volunteers) to see if the imaging drug 18F-NOS can help di…

This early-stage study involves 40 healthy adults to see how the body handles ABBV-8736 when given as a shot under the skin compared to an IV infusion. Researchers will measure drug levels, safety, and side effects. Participants do not have any disease, and the study is not inten…

This early-stage study looks at how a new drug called ABBV-295 interacts with common birth control pills in healthy adult women who are overweight or obese. The goal is to check for side effects and measure drug levels in the body. About 20 women will take part, and the results w…

This early-stage study is testing a new drug, JUV-161, in 72 healthy adults to see if it is safe and how the body processes it. Participants receive either the drug or a placebo by injection. The study does not aim to treat any disease, but the results will help plan future trial…

This study uses special PET scans to look for signs of inflammation in the brains of people with Alzheimer's disease or mild cognitive impairment, compared to healthy volunteers. Nine participants will receive an investigational radioactive tracer called [18F]NOS, and some may al…

This early-stage study is testing a new drug called ABBV-701 in about 100 healthy adults from Western and Asian backgrounds. The goal is to check its safety, how the body processes it, and whether it triggers an immune response. Participants receive a single dose and are monitore…

This early-stage study tests the safety of an experimental drug, ALN-F1202, in 56 healthy adults. The drug aims to lower a clotting factor, but this trial only checks for side effects and how the body processes the drug. Participants receive a single dose and are monitored closel…

This study looks at how healthy adults absorb and process three different ketone supplements (monoester, tri-ester, and salt). Researchers will measure ketone levels in the blood and check for any stomach discomfort or side effects. The goal is simply to gather information, not t…

This early-stage study looks at how a new drug called ABBV-932 moves through the body when taken with another drug, itraconazole. Twenty healthy adults will take both drugs and have their blood levels measured. The goal is to check for side effects and see if itraconazole changes…