GRAM NEGATIVE INFECTIONS
Clinical trials for GRAM NEGATIVE INFECTIONS explained in plain language.
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New antibiotic combo vaborem tested in kids for tough infections
Disease control Recruiting nowThis study is testing the safety and how the body handles Vaborem, a combination of two antibiotics (meropenem and vaborbactam), in children from birth to under 18 years old who have serious Gram-negative bacterial infections. All 44 participants will receive the drug intravenous…
Matched conditions: GRAM NEGATIVE INFECTIONS
Phase: PHASE2 • Sponsor: Menarini Group • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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Double antibiotic attack: could a Two-Drug combo beat severe infections faster?
Disease control Recruiting nowThis study tests whether adding a second antibiotic (fosfomycin) to the standard antibiotic (ceftazidime) helps people with severe gram-negative infections recover faster. About 100 hospitalized adults will be randomly assigned to get either the combo or the standard drug plus a …
Matched conditions: GRAM NEGATIVE INFECTIONS
Phase: PHASE3 • Sponsor: Angela HUTTNER • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Can a rapid test help doctors pick the right antibiotic faster?
Knowledge-focused Recruiting nowThis study tests whether a rapid lab test can help doctors choose the right antibiotic sooner for patients with bloodstream infections. About 400 adults with positive blood cultures will be randomly assigned to either the rapid test or standard testing. The goal is to see if the …
Matched conditions: GRAM NEGATIVE INFECTIONS
Phase: NA • Sponsor: Istituto Clinico Humanitas • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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Scientists seek best dose of Last-Resort antibiotics for superbug infections
Knowledge-focused Recruiting nowThis observational study is looking at how two antibiotics, ceftazidime/avibactam and fosfomycin, work in the body to treat infections caused by carbapenem-resistant Enterobacterales (CRE), a type of superbug. Researchers will monitor 60 adult patients to see if the drug levels i…
Matched conditions: GRAM NEGATIVE INFECTIONS
Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Could shorter antibiotic courses be safer for blood cancer patients?
Knowledge-focused Recruiting nowThis study looks at whether blood cancer patients with a serious infection can safely stop antibiotics sooner if they are stable for 72 hours, instead of the usual 10-day course. About 172 adults will be randomly assigned to either a personalized short course or standard long cou…
Matched conditions: GRAM NEGATIVE INFECTIONS
Phase: NA • Sponsor: Humanitas University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC