Could shorter antibiotic courses be safer for blood cancer patients?

NCT ID NCT07372131

First seen Jan 31, 2026 · Last updated Jun 18, 2026 · Updated 25 times

Summary

This study looks at whether blood cancer patients with a serious infection can safely stop antibiotics sooner if they are stable for 72 hours, instead of the usual 10-day course. About 172 adults will be randomly assigned to either a personalized short course or standard long course. The goal is to see if shorter treatment reduces antibiotic use and side effects without increasing risks like infection return or death.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Microbiology and Virology - IRCCS Humanitas Research Hospital

    RECRUITING

    Rozzano, Milan, 20089, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

bacterial infectious disease with sepsis Febrile Neutropenia gram-negative bacterial infections hematopoietic and lymphoid cell neoplasm Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.