GRAFT FAILURE
Clinical trials for GRAFT FAILURE explained in plain language.
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Could a cancer drug make stem cell transplants safer for sickle cell patients?
Disease control Recruiting nowThis study tests whether adding the drug ruxolitinib to a standard stem cell transplant can prevent graft failure in children and young adults with severe sickle cell disease. Up to 24 participants will receive the drug during conditioning and be followed for two years after tran…
Matched conditions: GRAFT FAILURE
Phase: PHASE1, PHASE2 • Sponsor: Arkansas Children's Hospital Research Institute • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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New stem cell transplant trial aims to treat sickle cell disease and other blood disorders
Disease control Recruiting nowThis phase 2 trial tests a stem cell transplant from a donor for people with high-risk sickle cell disease, thalassemia, and other red blood cell disorders. Participants receive drugs and low-dose radiation before the transplant to help the new cells take hold. The study will tra…
Matched conditions: GRAFT FAILURE
Phase: PHASE2 • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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New drug aims to stop transplant rejection in High-Risk patients
Disease control Recruiting nowThis early-stage study tests whether a drug called emapalumab can prevent the body from rejecting a stem cell transplant. The study will include 20 patients who are at high risk for rejection. Researchers will also study how the drug works in the body to improve future treatments…
Matched conditions: GRAFT FAILURE
Phase: EARLY_PHASE1 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Heart bypass patients may benefit from common arthritis drug
Disease control Recruiting nowThis study tests whether taking a low dose of colchicine (a medicine used for gout) every day for a year can prevent the new blood vessels created during heart bypass surgery from failing. About 100 adults who recently had bypass surgery will take colchicine or no extra treatment…
Matched conditions: GRAFT FAILURE
Phase: PHASE4 • Sponsor: Ruijin Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Which graft is best for women? new trial tests vein vs artery in bypass surgery
Disease control Recruiting nowThis study is for women under 75 who need heart bypass surgery for three blocked arteries. It compares two types of grafts for the second most important artery: a leg vein harvested with a special 'no-touch' technique versus a wrist artery. The goal is to see which graft stays op…
Matched conditions: GRAFT FAILURE
Phase: NA • Sponsor: University of Sao Paulo General Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Donor cell boost aims to rescue failed stem cell transplants
Disease control Recruiting nowThis study tests a procedure called a CD34+ selected donor cell boost for people whose stem cell transplant has not worked well (graft failure or poor function). The donor's blood stem cells are separated using a special system and then infused back into the patient to help resto…
Matched conditions: GRAFT FAILURE
Phase: NA • Sponsor: NYU Langone Health • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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New scan technique aims to solve mystery of failing heart bypass grafts
Knowledge-focused Recruiting nowThis study uses advanced total-body PET scans to look inside vein grafts after coronary artery bypass surgery. Researchers want to understand why some grafts fail, leading to heart attacks or strokes. They will scan 70 patients—some soon after surgery and others years later—to tr…
Matched conditions: GRAFT FAILURE
Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:10 UTC