GLIOMA, MALIGNANT

This early-stage study is testing the safety of a new treatment for aggressive brain tumors called high-grade glioma. Doctors are using specially engineered stem cells that carry a virus designed to target and kill cancer cells. The treatment is given directly into the brain mult…

This study is testing a new oral drug called TNG456, both alone and combined with another cancer drug (abemaciclib), in people with advanced solid tumors that have a specific genetic change called MTAP loss. The main goals are to find safe doses and see if the treatment can shrin…

This early-stage study is testing the safety and best dose of an experimental drug called CUE-102 in adults whose glioblastoma brain cancer has returned for the first time. CUE-102 is designed to activate the body's immune system to fight the tumor. The study will enroll about 18…

This study is testing whether a special type of PET scan using a tracer called 18F-fluciclovine can help doctors more accurately tell if a child's aggressive brain tumor is actually growing again or if the changes seen on a regular MRI are just a temporary reaction to treatment. …

This study is testing whether a new type of brain scan can help doctors better see how well treatments are working for children and young adults with low-grade brain tumors. Participants will get the special scan before starting treatment and again at 3 months and 1 year. Researc…

This study is testing a remote brain training program designed to help adults with specific types of brain tumors (grade 2 or 3 diffuse glioma) who are experiencing memory, attention, or thinking problems. The program combines online exercises with video calls with a specialist. …

This early study is testing whether an experimental oral drug called DSP-0390 can reach brain tumors in sufficient amounts and affect tumor cell metabolism. Researchers will give the drug for about two weeks to 20 patients with specific types of brain tumors (grade II/III gliomas…