GLIOBLASTOMA MULTIFORME (GBM)
Clinical trials for GLIOBLASTOMA MULTIFORME (GBM) explained in plain language.
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Immune cells injected into brain to fight tumors: new trial launches
Disease control Recruiting nowThis study tests a new treatment using natural killer (NK) cells, a type of immune cell, for adults with malignant brain tumors that have not responded to standard therapies. The NK cells are grown in a lab and then given through a vein and directly into the brain. The main goal …
Matched conditions: GLIOBLASTOMA MULTIFORME (GBM)
Phase: NA • Sponsor: Peking University Third Hospital • Aim: Disease control
Last updated May 16, 2026 23:52 UTC
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New drug duo takes on deadly brain cancer in early trial
Disease control Recruiting nowThis trial tests two drugs, avutometinib and defactinib, alone or with a third drug (temozolomide), in people with aggressive brain tumors like glioblastoma. The goal is to see if the combination is safe and can shrink tumors or slow their growth. About 182 adults with recurrent …
Matched conditions: GLIOBLASTOMA MULTIFORME (GBM)
Phase: PHASE1, PHASE2 • Sponsor: Institute of Cancer Research, United Kingdom • Aim: Disease control
Last updated May 16, 2026 23:47 UTC
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New combo attack on brain tumours shows promise in early trial
Disease control Recruiting nowThis study tests a new drug called paxalisib combined with standard chemotherapy (temozolomide) in people with aggressive brain tumours like glioblastoma. The goal is to see if the combination is safe and can slow tumour growth. About 64 adults will take part, and researchers wil…
Matched conditions: GLIOBLASTOMA MULTIFORME (GBM)
Phase: PHASE1, PHASE2 • Sponsor: Institute of Cancer Research, United Kingdom • Aim: Disease control
Last updated May 16, 2026 23:37 UTC
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New drug KESONOTIDE™ enters human trials for multiple cancers
Disease control Recruiting nowThis study tests a new drug, KESONOTIDE™, in people with advanced solid tumors like prostate, breast, lung, ovarian, pancreatic, skin cancer, or glioblastoma. The main goal is to check if the drug is safe and tolerable, and to find the right dose. About 80 adults will take part i…
Matched conditions: GLIOBLASTOMA MULTIFORME (GBM)
Phase: PHASE1, PHASE2 • Sponsor: Filamon LTD • Aim: Disease control
Last updated May 16, 2026 23:37 UTC
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New hope for aggressive brain cancer: combo therapy enters phase 2 trial
Disease control Recruiting nowThis study tests whether adding silevertinib (an oral targeted therapy) to standard chemotherapy (temozolomide) helps people with a specific type of newly diagnosed glioblastoma live longer without their cancer growing. About 162 adults whose tumors have certain genetic markers (…
Matched conditions: GLIOBLASTOMA MULTIFORME (GBM)
Phase: PHASE2 • Sponsor: Black Diamond Therapeutics, Inc. • Aim: Disease control
Last updated May 11, 2026 20:54 UTC
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Sound wave helmet could help chemo reach brain tumors
Disease control Recruiting nowThis early-stage trial tests a special helmet that uses sound waves to temporarily open the blood-brain barrier, allowing chemotherapy to better reach aggressive brain tumors called glioblastoma. Ten adults who have already completed initial treatment will receive the helmet trea…
Matched conditions: GLIOBLASTOMA MULTIFORME (GBM)
Phase: PHASE1 • Sponsor: Sunnybrook Health Sciences Centre • Aim: Disease control
Last updated May 11, 2026 20:39 UTC