GENERALIZED MYASTHENIA GRAVIS (GMG)

This study is testing two drugs, efgartigimod and empasiprubart, given by IV, to see if they are safe and work well for people with myasthenia gravis (MG). The goal is to reduce side effects and improve quality of life. About 70 adults with MG are being recruited.

This study tests whether adding empasiprubart to the existing drug efgartigimod can improve symptoms and daily function in people with generalized myasthenia gravis who still have symptoms on efgartigimod alone. About 70 participants will receive both drugs intravenously. The mai…

This study follows 100 adults in Italy with generalized myasthenia gravis who are starting efgartigimod as part of their routine care. Researchers will track changes in symptoms and daily activities over up to 23 months using patient reports and doctor assessments. The goal is to…

This study tests a daily injection called zilucoplan in 15 people hospitalized with severe myasthenia gravis (MG) flare-ups. The goal is to see if the drug can quickly improve daily living activities, like breathing and swallowing, within two weeks. Participants receive the injec…

This early study tests a new treatment called GC012F, made from a patient's own immune cells (CAR-T cells), for people with refractory generalized myasthenia gravis that hasn't responded to standard therapies. Six participants will receive a single infusion of these modified cell…

This study watches how doctors in Russia treat adults with a rare muscle-weakening disease called generalized myasthenia gravis (gMG). It does not test any new drug. Instead, it collects information from medical records and routine check-ups for about 450 people over time. The go…

This study follows 75 pregnant women who have taken Ultomiris (ravulizumab) for conditions like PNH or aHUS. Researchers will track pregnancy outcomes and baby health up to one year after birth. The goal is to gather safety information, not to test a new treatment.