New drug combo aims to ease myasthenia gravis symptoms
NCT ID NCT07294170
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study is testing two drugs, efgartigimod and empasiprubart, given by IV, to see if they are safe and work well for people with myasthenia gravis (MG). The goal is to reduce side effects and improve quality of life. About 70 adults with MG are being recruited.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Efgartigimod and empasiprubart (given as intravenous infusions)
What this could lead to
If successful, this could point toward better treatment options for myasthenia gravis with fewer side effects and improved quality of life.
What could go wrong
This is an early Phase 2a proof-of-concept study with only 70 participants, so results may not apply to everyone. The drugs may not work as hoped or could cause unexpected side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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ASST Papa Giovanni XXIII - Ospedale Papa Giovanni XXIII
RECRUITINGBergamo, Lombardy, 24127, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centrum Medyczne Neurologia Slaska
RECRUITINGKatowice, Silesian Voivodeship, 40-689, Poland
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Dent Neurologic Institute - Amherst
RECRUITINGAmherst, New York, 14226, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Duke Early Phase Clinical Research Unit - PPDS
ACTIVE_NOT_RECRUITINGDurham, North Carolina, 27710-0001, United States
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Erlanger Health System
RECRUITINGColumbia, Maryland, 21044, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Erlanger Health System
RECRUITINGChattanooga, Tennessee, 37403-2136, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Fondazione IRCCS Istituto Neurologico Carlo Besta
ACTIVE_NOT_RECRUITINGMilan, Lombardy, 20133, Italy
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Henry Ford Health System
ACTIVE_NOT_RECRUITINGDetroit, Michigan, 48202-2608, United States
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Hospital Regional Universitario de Malaga - Hospital General
RECRUITINGMálaga, Malaga, 340120, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Krakowska Akademia Neurologii Sp. z o.o.
RECRUITINGKrakow, Lesser Poland Voivodeship, 31-505, Poland
Contact Phone: •••-•••-•••• Email: •••••@•••••
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MICS Centrum Medyczne Bydgoszcz
RECRUITINGBydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-065, Poland
Contact Phone: •••-•••-•••• Email: •••••@•••••
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National Neuromuscular Research Institute
RECRUITINGAustin, Texas, 78759, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ohio State Martha Morehouse Outpatient Care
RECRUITINGColumbus, Ohio, 43221-3502, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Profound Research LLC - Carlsbad
RECRUITINGCarlsbad, California, 92011, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UZ Leuven - PPDS
RECRUITINGLeuven, 3000, Belgium
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of South Florida
RECRUITINGTampa, Florida, 33620, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Texas- San Antonio - Health Science Center - PPDS
RECRUITINGSan Antonio, Texas, 78229, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Visionary Investigators Network
RECRUITINGMiami, Florida, 33133, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••