Real-World study tracks Efgartigimod's impact on myasthenia gravis symptoms

NCT ID NCT07595653

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 100 adults in Italy with generalized myasthenia gravis who are starting efgartigimod as part of their routine care. Researchers will track changes in symptoms and daily activities over up to 23 months using patient reports and doctor assessments. The goal is to see how well the drug works in real life, not just in controlled trials.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
efgartigimod alfa
What this could lead to
If successful, this study could show that efgartigimod improves daily functioning and symptom control for people with generalized myasthenia gravis in real-world settings.
What could go wrong
This is an observational study, not a controlled trial, so results may be less definitive. It is also limited to Italian patients and a specific antibody type, which may not apply to everyone.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • A.O.U. Careggi

    RECRUITING

    Florence, 50134, Italy

    Contact Email: •••••@•••••

  • A.O.U. Consorziale Policlinico

    RECRUITING

    Bari, 70124, Italy

    Contact Email: •••••@•••••

  • A.O.U. Pisana

    RECRUITING

    Pisa, 56124, Italy

    Contact Email: •••••@•••••

  • A.O.U. Policlinico G. Martino

    RECRUITING

    Messina, 98124, Italy

    Contact Email: •••••@•••••

  • A.O.U. Policlinico Universitario

    RECRUITING

    Monserrato, 09042, Italy

    Contact Email: •••••@•••••

  • A.O.U. Renato Dulbecco

    RECRUITING

    Catanzaro, 88100, Italy

    Contact Email: •••••@•••••

  • A.O.U. San Giovanni di Dio e Ruggi D'Aragona

    RECRUITING

    Salerno, 84131, Italy

    Contact Email: •••••@•••••

  • A.O.U. San Luigi Gonzaga

    RECRUITING

    Orbassano, 10043, Italy

    Contact Email: •••••@•••••

  • A.O.U. Sassari

    RECRUITING

    Sassari, 07100, Italy

    Contact Email: •••••@•••••

  • A.O.U. Università della Campania L. Vanvitelli

    RECRUITING

    Naples, 80138, Italy

    Contact Email: •••••@•••••

  • AORN A. Cardarelli

    RECRUITING

    Naples, 80131, Italy

    Contact Email: •••••@•••••

  • AOUI Verona - Policlinico G.B. Rossi

    RECRUITING

    Verona, 37134, Italy

    Contact Email: •••••@•••••

  • ASST GOM Niguarda

    RECRUITING

    Milan, 20162, Italy

    Contact Email: •••••@•••••

  • ASST Papa Giovanni XXIII

    RECRUITING

    Bergamo, 24127, Italy

    Contact Email: •••••@•••••

  • Azienda Ospedale Università Padova

    RECRUITING

    Padova, 35128, Italy

    Contact Email: •••••@•••••

  • Azienda Ospedaliera Perugia

    RECRUITING

    Perugia, 06132, Italy

    Contact Email: •••••@•••••

  • Azienda Ospedaliero Universitaria delle Marche

    RECRUITING

    Ancona, 60126, Italy

    Contact Email: •••••@•••••

  • Fondazione PTV Policlinico Tor Vergata

    RECRUITING

    Roma, 00133, Italy

    Contact Email: •••••@•••••

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS

    RECRUITING

    Roma, 00168, Italy

    Contact Email: •••••@•••••

  • IRCCS Cà Granda Ospedale Maggiore Policlinico

    RECRUITING

    Milan, 20122, Italy

    Contact Email: •••••@•••••

  • IRCCS Fondazione Casa Sollievo della Sofferenza

    RECRUITING

    San Giovanni Rotondo, 71013, Italy

    Contact Email: •••••@•••••

  • IRCCS Fondazione Mondino

    RECRUITING

    Pavia, 27100, Italy

    Contact Email: •••••@•••••

  • IRCCS Istituto Neurologico Carlo Besta

    RECRUITING

    Milan, 20133, Italy

    Contact Email: •••••@•••••

  • IRCCS Ospedale Policlinico San Martino

    RECRUITING

    Genova, 16132, Italy

    Contact Email: •••••@•••••

  • Ospedale Bellaria

    RECRUITING

    Bologna, 40139, Italy

    Contact Email: •••••@•••••

  • Ospedale Ca' Foncello

    RECRUITING

    Treviso, 31100, Italy

    Contact Email: •••••@•••••

  • Ospedale Generale Regionale F. Miulli

    RECRUITING

    Acquaviva delle Fonti, 70021, Italy

    Contact Email: •••••@•••••

  • Ospedale San Raffaele

    RECRUITING

    Milan, 20132, Italy

    Contact Email: •••••@•••••

  • Ospedale Sant'Andrea

    RECRUITING

    Roma, 00189, Italy

    Contact Email: •••••@•••••

  • Ospedale degli Infermi

    RECRUITING

    Rimini, 47923, Italy

    Contact Email: •••••@•••••

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