FRAGILE X SYNDROME
Clinical trials for FRAGILE X SYNDROME explained in plain language.
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New drug shows promise for fragile x teens in landmark trial
Symptom relief CompletedThis study tested an experimental drug called BPN14770 in 163 teenage boys with Fragile X syndrome. The goal was to see if the drug could improve thinking skills and daily life abilities compared to a placebo. The trial had two parts: first to check how the drug moves through the…
Matched conditions: FRAGILE X SYNDROME
Phase: PHASE2, PHASE3 • Sponsor: Tetra Discovery Partners • Aim: Symptom relief
Last updated May 15, 2026 11:56 UTC
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CBD gel shows promise for fragile x behavior issues in major trial
Symptom relief CompletedThis study tested a CBD gel (ZYN002) applied to the skin in children, teens, and young adults with Fragile X Syndrome. The goal was to see if it could ease difficult behaviors like irritability and social withdrawal. 215 participants received either the gel or a placebo for up to…
Matched conditions: FRAGILE X SYNDROME
Phase: PHASE3 • Sponsor: Zynerba Pharmaceuticals, Inc. • Aim: Symptom relief
Last updated May 14, 2026 12:06 UTC
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Diabetes drug shows promise for fragile x symptoms in new trial
Symptom relief CompletedThis study tested if metformin, a common diabetes medicine, can help improve language, behavior, and weight control in people with Fragile X syndrome. 125 participants aged 6 to 35 were randomly assigned to receive metformin or a placebo for 4 months. The main goal was to see if …
Matched conditions: FRAGILE X SYNDROME
Phase: PHASE2 • Sponsor: University of Alberta • Aim: Symptom relief
Last updated May 13, 2026 16:01 UTC
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Brain wave study tests new drug in fragile x patients
Knowledge-focused CompletedThis study gave a single dose of gaboxadol or a placebo to 10 adult men with Fragile X Syndrome to measure changes in brain activity using EEG. The main goal was to see if the drug affects brain waves and to test whether research visits can be done at home. Participants took the …
Matched conditions: FRAGILE X SYNDROME
Phase: PHASE2 • Sponsor: Craig Erickson • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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NIH study explores rare genetic conditions in kids to boost research skills
Knowledge-focused CompletedThis study enrolled 96 children with known or suspected genetic disorders, including conditions like autism and Fragile X syndrome. The main goal was to give clinic staff hands-on experience and explore new research methods, not to provide treatment. Participants had medical exam…
Matched conditions: FRAGILE X SYNDROME
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) • Aim: Knowledge-focused
Last updated May 06, 2026 16:01 UTC