FRAGILE X SYNDROME
Clinical trials for FRAGILE X SYNDROME explained in plain language.
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Promising fragile x drug moves to Long-Term safety check
Disease control OngoingThis study looks at the long-term safety of a drug called BPN14770 in people with Fragile X syndrome. It includes about 314 adults and teens who already completed earlier studies of the drug. Everyone in this study will receive the drug for up to 4 years, and researchers will mon…
Matched conditions: FRAGILE X SYNDROME
Phase: PHASE3 • Sponsor: Tetra Discovery Partners • Aim: Disease control
Last updated May 12, 2026 13:43 UTC
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CBD gel shows promise for fragile x in Long-Term trial
Symptom relief ENROLLING_BY_INVITATIONThis study looks at the long-term safety of a CBD gel (ZYN002) applied to the skin for children, teens, and young adults with Fragile X syndrome. Participants apply the gel twice daily for 52 weeks. The goal is to see if the gel is safe and helps with symptoms over time.
Matched conditions: FRAGILE X SYNDROME
Phase: PHASE2, PHASE3 • Sponsor: Zynerba Pharmaceuticals, Inc. • Aim: Symptom relief
Last updated May 17, 2026 02:59 UTC
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Can a tablet test track how stimulants help kids with intellectual disability?
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether a set of thinking and attention tests can measure changes caused by a stimulant medication in children aged 6 to 17 who have both intellectual disability and ADHD. About 68 participants will receive either the medication or a placebo, then switch after…
Matched conditions: FRAGILE X SYNDROME
Phase: PHASE1 • Sponsor: University of California, Davis • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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Brain wave study tests three drugs for fragile x
Knowledge-focused OngoingThis study looks at how single doses of baclofen, roflumilast, and memantine affect brain activity and behavior in 45 adults with Fragile X Syndrome. Participants take each drug or a placebo on separate days, and researchers measure changes in brain waves and clinical symptoms. T…
Matched conditions: FRAGILE X SYNDROME
Phase: PHASE2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:02 UTC