New drug shows promise for fragile x symptoms in small trial

NCT ID NCT06413537

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a single dose of SPG601 in 10 adult men with Fragile X syndrome to see if it improves symptoms like attention and behavior. Participants were randomly assigned to receive either the drug or a placebo, and neither they nor their doctors knew which they got. The goal was to measure changes in clinical ratings, caregiver observations, and brain responses to sound.

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Conditions

The condition(s) this trial relates to.

fragile X syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States