ESTROGEN-RECEPTOR-POSITIVE BREAST CANCER
Clinical trials for ESTROGEN-RECEPTOR-POSITIVE BREAST CANCER explained in plain language.
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New combo therapy shows promise in preventing breast cancer return
Disease control CompletedThis study looked at whether shutting down the ovaries (ovarian suppression) and adding a drug called exemestane could better prevent breast cancer from coming back in premenopausal women with hormone-sensitive breast cancer. Over 3,000 women who had surgery took either tamoxifen…
Matched conditions: ESTROGEN-RECEPTOR-POSITIVE BREAST CANCER
Phase: PHASE3 • Sponsor: ETOP IBCSG Partners Foundation • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New drug combo shows promise for controlling advanced breast cancer
Disease control CompletedThis study tested a combination of two drugs, palbociclib and tamoxifen, as the first treatment for people with a certain type of advanced breast cancer (hormone receptor positive, HER2 negative). The goal was to see how long the cancer could be kept from growing. 49 participants…
Matched conditions: ESTROGEN-RECEPTOR-POSITIVE BREAST CANCER
Phase: PHASE2 • Sponsor: Oana Danciu, MD • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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New combo shows promise for older breast cancer patients
Disease control CompletedThis study looked at how well older adults (70+) with a common type of advanced breast cancer tolerate a combination of the targeted drug palbociclib and hormone therapy (letrozole or fulvestrant). The goal was to understand side effects and find factors beyond age that might pre…
Matched conditions: ESTROGEN-RECEPTOR-POSITIVE BREAST CANCER
Phase: PHASE2 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated May 06, 2026 16:01 UTC
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Shrinking tumors before surgery: a gentler approach for breast cancer?
Symptom relief CompletedThis study tested a new approach for older patients with early-stage hormone-positive breast cancer: giving a high dose of focused radiation before surgery instead of after. The goal was to shrink the tumor and reduce damage to healthy tissue. Twenty-two patients participated to …
Matched conditions: ESTROGEN-RECEPTOR-POSITIVE BREAST CANCER
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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Can a keto diet boost breast cancer treatment?
Symptom relief CompletedThis early-phase study tested whether a 2-week very low-carb (ketogenic) diet combined with the hormone therapy letrozole is feasible and tolerable for 31 postmenopausal women with early-stage estrogen receptor-positive breast cancer. The goal was to see if the diet could help re…
Matched conditions: ESTROGEN-RECEPTOR-POSITIVE BREAST CANCER
Phase: EARLY_PHASE1 • Sponsor: Vanderbilt-Ingram Cancer Center • Aim: Symptom relief
Last updated May 14, 2026 12:04 UTC