ENDOTHELIAL DYSFUNCTION

This study investigates whether a dietary supplement made from centella asiatica, also known as gotu kola, can improve the function of blood vessels in adults aged 50 to 85. Participants take either the herb or a placebo for four weeks, and researchers measure changes in blood ve…

This completed study tested whether resveratrol, a natural compound found in grapes and berries, can improve blood vessel health and blood sugar control in people with type 2 diabetes. 48 adults took either a resveratrol pill or a placebo daily for 12 weeks. Researchers measured …

This study looked at whether garlic supplements can improve blood vessel function and reduce inflammation in adults with kidney failure who are on hemodialysis. Fifty-eight patients took garlic extract or a placebo for a period of time. Researchers measured markers of inflammatio…

This study tested if a gentle electrical stimulation on the ear (transcutaneous vagal stimulation) could improve blood vessel function in 11 people with peripheral artery disease (PAD). The goal was to see if this non-invasive method could help blood vessels relax and work better…

This study looks at how eating a high-fat meal changes levels of certain fats in the blood called ceramides, and whether those changes affect blood vessel function. Healthy adults aged 18 to 40 will eat either a meal rich in long-chain fatty acids (which raise ceramides) or mediu…

This study looked at how blood vessel function relates to heart blockage in people with a genetic heart condition called hypertrophic cardiomyopathy. Researchers measured blood flow and vessel flexibility in 40 adults. The goal was to understand the connection, not to test a trea…

This completed study compared two anesthesia methods—general anesthesia and infraclavicular block—in 106 adults undergoing upper arm surgery with a tourniquet. Researchers measured markers of oxidative stress and blood vessel function to see which method causes less damage. The g…

This completed study looked at 168 adults with a history of trauma to see if PTSD harms blood vessel function, which could raise heart disease risk. Participants completed behavioral tasks measuring fear and attention, and had their blood vessel health checked. The goal is to und…

This completed study looked at 111 people to see if measuring blood flow in the skin can help assess cardiovascular risk in those with resistant hypertension (high blood pressure that doesn't respond to multiple drugs). Researchers used a laser device to check how well tiny blood…

This study tested whether nicotine in electronic hookah (e-hookah) affects blood vessel function. Thirty-three healthy young adults who already used hookah or e-cigarettes vaped e-hookah with or without nicotine in separate sessions. Researchers measured blood vessel dilation and…

This study tested whether a daily supplement called COMP-4 could improve blood vessel function and reduce markers of aging in 32 healthy adults aged 18-39. Participants took the supplement for 14 days, and researchers measured blood vessel dilation using ultrasound and checked bl…

This small, early study tested whether drinking beetroot juice (which is rich in natural nitrates) could improve artery stiffness and brain blood vessel function in adults aged 50 to 79. Sixteen participants were randomly given either nitrate-rich or nitrate-depleted beetroot jui…

This completed study looked at 51 people having surgery to remove plaque from their neck arteries. Researchers checked the plaque for oral bacteria and measured mitochondrial DNA. The goal was to see if mouth germs might play a role in artery disease. No treatment was given—it wa…

This study looked at whether a score called Modified EASIX, calculated from routine blood tests, can help predict how severe erectile dysfunction (ED) is. Researchers reviewed medical records of 380 men aged 18-65 and compared the score between those with and without ED. No treat…

This completed study investigated why patients with Cytochrome P450 Oxidoreductase (POR) deficiency, a rare genetic condition, often develop high blood pressure and blood vessel damage. Researchers compared 51 participants (patients and healthy controls) using 24-hour blood press…