DISORDERS OF CONSCIOUSNESS

This early study tests whether gentle electrical stimulation deep inside the brain can help people with long-term disorders of consciousness regain awareness. Two people with brain injuries from causes like cardiac arrest or stroke will receive the stimulation. The main goal is t…

This study looks at whether the way people blink their eyes naturally can help doctors tell the difference between two states of consciousness after severe brain injury: unresponsive wakefulness and minimally conscious state. Researchers will measure blink rate, size, and timing …

This study explores whether measuring brain activity during a gentle rectal balloon stretch can help doctors tell the difference between patients who are minimally conscious and those who appear unresponsive but may have hidden awareness. About 45 adults with long-term consciousn…

This study tests a new, non-invasive brain stimulation technique called theta-burst patterned temporal interference stimulation (tTIs) to see if it can improve awareness in people with disorders of consciousness, such as vegetative or minimally conscious states. About 136 adults …

This study tests a safe, non-invasive technique called transcutaneous auricular vagus nerve stimulation (taVNS) in 20 people with disorders of consciousness (vegetative state or minimally conscious state) after severe brain injury. Participants receive two 20-minute ear stimulati…

This study looks at whether people with disorders of consciousness (like coma or minimally conscious state) can form and recall memories. Researchers will use EEG and skin sensors to detect brain activity linked to memory, without needing the patient to respond. The goal is to be…

This study explores whether ultrasound, a low-cost and widely available tool, can help doctors better understand and treat people with disorders of consciousness (DOC), such as coma or a minimally conscious state. Researchers will use brain ultrasound to measure brain activity an…