Could brain zaps wake the unresponsive? tiny trial begins

NCT ID NCT07228286

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early study tests whether implanting electrodes deep in the brain (thalamus) can safely help people with long-term disorders of consciousness. Only 2 participants will be enrolled, and the main goal is to check safety and see if awareness improves using a standard behavioral scale.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

deep brain stimulation (DBS) electrodes implanted in the thalamus

What this could lead to

If successful, this could point toward a new way to help people with long-term consciousness disorders regain some awareness.

What could go wrong

This is a very early, tiny trial (only 2 people) focused on safety. It may not show clear benefit, and brain surgery carries risks like infection or bleeding.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DISORDERS OF CONSCIOUSNESS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

brain injury Consciousness Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••