Could brain zaps wake the unresponsive? tiny trial begins

NCT ID NCT07228286

Recruiting now Disease control Sponsor: Samuel Snider, MD Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early study tests whether implanting electrodes deep in the brain (thalamus) can safely help people with long-term disorders of consciousness. Only 2 participants will be enrolled, and the main goal is to check safety and see if awareness improves using a standard behavioral scale.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: deep brain stimulation (DBS) electrodes implanted in the thalamus
What this could lead to: If successful, this could point toward a new way to help people with long-term consciousness disorders regain some awareness.
What could go wrong: This is a very early, tiny trial (only 2 people) focused on safety. It may not show clear benefit, and brain surgery carries risks like infection or bleeding.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

brain injury Consciousness Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DISORDERS OF CONSCIOUSNESS

Contacts and locations

Locations

Brigham and Women's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.