Zap to awaken: new brain stimulation trial hopes to reach patients trapped in their minds

NCT ID NCT07539740

First seen Apr 21, 2026 · Last updated May 06, 2026 · Updated 5 times

Summary

This study tests a new, non-invasive brain stimulation method called theta-burst patterned temporal interference stimulation (tTIs) to see if it can improve awareness in people with disorders of consciousness, such as vegetative or minimally conscious states. About 136 adults will receive either real tTIs or a sham (fake) stimulation twice a day for 5 days. Researchers will measure changes in consciousness using standard tests and brain activity recordings before and after treatment, and follow up by phone for 6 months.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Zhujiang Hospital of Southern Medical University

    RECRUITING

    Guangzhou, Guangdong, 510280, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.