Could a zapping helmet wake the unresponsive?

NCT ID NCT07539740

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new, non-invasive brain stimulation method called theta-burst patterned temporal interference stimulation (tTIs) to see if it can improve awareness in people with disorders of consciousness, such as vegetative or minimally conscious states. About 136 adults will receive either real tTIs or a fake (sham) stimulation twice daily for 5 days. Researchers will measure changes in consciousness using standard behavioral scales and brain activity tests, and follow up for 6 months.

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Conditions

The condition(s) this trial relates to.

Consciousness Disorders Persistent Vegetative State

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Zhujiang Hospital of Southern Medical University

    RECRUITING

    Guangzhou, Guangdong, 510280, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••