Rectal balloon test may reveal hidden consciousness

NCT ID NCT07208942

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study explores whether measuring brain activity during a brief rectal balloon inflation can help doctors tell the difference between patients who are minimally conscious and those who are unresponsive. Researchers will record EEGs in 45 patients with disorders of consciousness and healthy volunteers. The goal is to develop an objective test for diagnosing levels of awareness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Rectal balloon stimulation device

What this could lead to

If successful, this could provide a new, objective way to classify consciousness levels in patients with disorders like unresponsive wakefulness syndrome or minimally conscious state.

What could go wrong

This is a small, early-stage study with only 45 participants. The approach is experimental and may not reliably distinguish between patient groups or translate to broader clinical use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Consciousness Disorders disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hangzhou Normal University

    ENROLLING_BY_INVITATION

    Hangzhou, Zhejiang, 310000, China

  • The Second People's Hospital of Hefei

    RECRUITING

    Hefei, Anhui, 230000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••