Blink of an eye: new study tests simple test for consciousness disorders

NCT ID NCT06323031

Recruiting now Diagnosis Sponsor: Fondazione Don Carlo Gnocchi ETS Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 14, 2026 · Updated 2 times

Summary

This study looks at whether spontaneous eye blinking can help doctors tell the difference between two types of consciousness disorders: unresponsive wakefulness syndrome and minimally conscious state. Researchers will measure blinking patterns in 70 patients across 8 European centers. The goal is to see if blinking can serve as a simple, non-invasive diagnostic and prognostic tool.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could provide a simple, non-invasive way to help doctors diagnose and predict recovery in patients with disorders of consciousness.
What could go wrong: This is an early observational study with only 70 participants, so results may not apply to all patients. Eye blinking may not be a reliable marker across different individuals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DISORDERS OF CONSCIOUSNESS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Consciousness Disorders disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DISORDERS OF CONSCIOUSNESS

Contacts and locations

Locations

Coma Science Group, GIGA-Consciousness, University of Liege
NOT_YET_RECRUITING

Liège, Belgium, 4000, Belgium
Dipartimento di Neurologia, LMU Hospital, LMU Munich
RECRUITING

Munich, Germany, 81377, Germany
IRCCS Fondazione Don Gnocchi ONLUS
RECRUITING

Florence, Italy, 50143, Italy
IRCCS Santa Maria Nascente Fondazione Don Gnocchi ONLUS
RECRUITING

Milan, Italy, 20148, Italy
Instituto de Rehabilitación Neurológica IRENEA
RECRUITING

Valencia, Spain, 46007, Spain
Polo Specialistico Riabilitativo Fondazione Don Carlo Gnocchi ONLUS
RECRUITING

Sant'Angelo dei Lombardi, AV, 83054, Italy
Therapiezentrum Burgau
RECRUITING

Burgau, Germany, 89331, Germany
Unità Gravi Cerebrolesioni - Dipartimento Neuroscienze - Azienda Ospedaliera - Universitaria Ferrara
RECRUITING

Ferrara, Italy, 44124, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.