DIFFUSE MIDLINE GLIOMA
Clinical trials for DIFFUSE MIDLINE GLIOMA explained in plain language.
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New brain cancer drug shows promise in early trial
Disease control TerminatedThis early-phase study tests whether adding a drug called S-Gboxin to standard treatment can help people with glioblastoma, a fast-growing brain cancer. The drug works by cutting off the energy supply to cancer cells. Ten patients with recurrent or progressive disease will receiv…
Matched conditions: DIFFUSE MIDLINE GLIOMA
Phase: PHASE1 • Sponsor: Petrov, Andrey • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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New drug combo shows promise for kids with brain cancer
Disease control OngoingThis early-phase trial is testing two drugs, avelumab and lenvatinib, together in children with brain tumors that have not responded to prior treatment. The study has two parts: first, finding a safe dose, and second, seeing if the combination can slow tumor growth. Only 17 child…
Matched conditions: DIFFUSE MIDLINE GLIOMA
Phase: PHASE1 • Sponsor: EMD Serono Research & Development Institute, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Vitamin c and iron combo takes on brain cancer in early trial
Disease control OngoingThis early-phase trial tests whether adding high-dose vitamin C and an iron supplement (ferumoxytol) to standard radiation and chemotherapy can help adults with newly diagnosed glioblastoma, an aggressive brain tumor. The study includes 17 participants and focuses on finding a sa…
Matched conditions: DIFFUSE MIDLINE GLIOMA
Phase: PHASE1 • Sponsor: Bryan Allen • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Engineered immune cells injected directly into the brain take on childhood tumors
Disease control OngoingThis early-stage trial tests a new treatment called SC-CAR4BRAIN for children and young adults with certain aggressive brain tumors, including DIPG and DMG. The treatment involves taking a patient's own immune T cells, engineering them in a lab to recognize and attack tumor cells…
Matched conditions: DIFFUSE MIDLINE GLIOMA
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Can a pill get into brain tumors? tiny study aims to find out
Knowledge-focused OngoingThis early study tests whether the drug abemaciclib can be measured inside brain tumors after being taken by mouth. One person aged 18–39 with a recurrent high-grade glioma or diffuse midline glioma will take the drug for 4.5 days before surgery. During surgery, a small tube is p…
Matched conditions: DIFFUSE MIDLINE GLIOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC