DIALYSIS

This study tested a new drug called AP301 in 474 adults with end-stage kidney disease on dialysis who have high phosphorus levels. The goal was to see if AP301 can safely lower phosphorus better than the current standard treatment, sevelamer carbonate. Participants received eithe…

This study looked at the long-term safety of a drug called MCI-196 in 116 adults with advanced kidney disease who are on dialysis and have high phosphate levels. The goal was to see if the drug is safe to take over time and if it helps control phosphate levels. Participants took …

This study tested a drug called MCI-196 in 642 adults on dialysis who had high phosphorus and cholesterol levels. The goal was to see if the drug could safely lower these levels, which are linked to heart problems. Participants took either MCI-196 or a placebo for 12 weeks after …

This study tested a drug called MCI-196 in 245 adults on dialysis with high phosphorus levels. After a 12-week dose adjustment period, some patients switched to a placebo to see if MCI-196 kept phosphorus levels lower. The goal was to manage a common complication of kidney failur…

This study tested an automated insulin delivery system (a smart pump) in 15 adults with type 1 or type 2 diabetes who also have advanced kidney disease or are on dialysis. Participants used the system for 8 weeks, then switched to their usual care for another 8 weeks. The goal wa…

This study tested the long-term safety of a drug called MCI-196 in 632 adults with chronic kidney disease on dialysis who also have high phosphorus levels. Participants took the drug for up to 52 weeks to see how it affected their blood phosphorus and cholesterol. The goal was to…

This study looked at 60 adults on long-term dialysis to see if having shorter, more frequent sessions (2 hours, 6 times a week) is better than standard sessions (4 hours, 3 times a week) at preventing dangerous drops in blood flow to the legs during treatment. The goal was to fin…

This study tested a communication tool called 'Best Case/Worst Case' to help older adults with advanced kidney disease talk with their doctors about treatment choices. About 320 patients and their doctors took part, with some doctors trained to use the tool and others not. The go…

This study aimed to find out how often patients in Reunion Island start dialysis as an emergency and what social or medical factors contribute to it. Researchers followed 233 adults beginning dialysis at local centers. The goal was to gather information, not to test a new treatme…

This study looked at 167 adults with chronic kidney disease who were on either hemodialysis or peritoneal dialysis. Researchers compared their blood levels of calcium, phosphorus, and other minerals to see how each dialysis type affects bone and mineral health. The goal was to be…