DERMATOMYOSITIS
Clinical trials for DERMATOMYOSITIS explained in plain language.
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New hope for rare muscle diseases: drug shows promise in long-term trial
Disease control CompletedThis study looked at the long-term safety and effectiveness of a drug called KZR-616 in 18 adults with active polymyositis or dermatomyositis, rare diseases that cause muscle inflammation and weakness. Participants had already completed a previous study and continued taking KZR-6…
Matched conditions: DERMATOMYOSITIS
Phase: PHASE2 • Sponsor: Kezar Life Sciences, Inc. • Aim: Disease control
Last updated May 17, 2026 04:14 UTC
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New drug shows promise for rare muscle diseases
Disease control CompletedThis study tested an experimental drug called KZR-616 in 25 adults with active polymyositis or dermatomyositis, two rare diseases that cause muscle inflammation and weakness. Participants received weekly injections of the drug or a placebo for 16 weeks, then switched to the other…
Matched conditions: DERMATOMYOSITIS
Phase: PHASE2 • Sponsor: Kezar Life Sciences, Inc. • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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Full-Body MRI may replace painful biopsies for muscle disease diagnosis
Diagnosis CompletedThis study looked at whether whole body magnetic resonance imaging (MRI) can correctly identify inflammatory muscle diseases like myositis. Researchers tested 139 people with suspected muscle inflammation to see how well MRI results matched the standard method of muscle biopsy. T…
Matched conditions: DERMATOMYOSITIS
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Diagnosis
Last updated May 17, 2026 04:12 UTC
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Personalized rehab shows promise for rare muscle diseases
Symptom relief CompletedThis study tested whether a custom rehabilitation program can improve daily function and quality of life for people with dermatomyositis or polymyositis, two rare diseases that cause muscle inflammation and weakness. Eighty adults with stable muscle impairment took part. The prog…
Matched conditions: DERMATOMYOSITIS
Phase: PHASE2 • Sponsor: University Hospital, Lille • Aim: Symptom relief
Last updated May 17, 2026 04:18 UTC
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Military mystery: why do some soldiers develop rare muscle disease?
Knowledge-focused CompletedThis study looked at why some military personnel develop myositis, a rare disease where the immune system attacks muscle tissue, causing weakness and pain. Researchers compared 37 people—some with myositis and some healthy—using questionnaires and blood samples to find possible e…
Matched conditions: DERMATOMYOSITIS
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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Scientists dig into genetic and environmental triggers of muscle autoimmune diseases
Knowledge-focused CompletedThis study looked at what causes autoimmune diseases that affect muscles and connective tissues, like myositis. Researchers studied 719 people, including patients, their relatives, and healthy volunteers, to find genetic and environmental risk factors. Participants gave blood sam…
Matched conditions: DERMATOMYOSITIS
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated May 13, 2026 16:03 UTC
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Simple muscle test could change how we track rare muscle diseases
Knowledge-focused CompletedThis study looked at a simple, low-cost test called the Myositis Functional Index-3 (FI-3) to see if it accurately measures muscle function in people with inflammatory myopathies (diseases that cause muscle weakness). Researchers compared it to advanced machines and also tested a…
Matched conditions: DERMATOMYOSITIS
Phase: NA • Sponsor: Federal University of Espirito Santo • Aim: Knowledge-focused
Last updated May 13, 2026 16:02 UTC