New drug shows promise for rare muscle disease

NCT ID NCT05669014

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested an experimental drug called daxdilimab in 12 adults with dermatomyositis or anti-synthetase myositis that wasn't well controlled by standard treatments. The goal was to see if the drug could reduce disease activity and skin symptoms, and help lower steroid use over 24 weeks. The trial compared daxdilimab to a placebo to measure safety and effectiveness.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acquired idiopathic inflammatory myopathy antisynthetase syndrome dermatomyositis myositis disease polymyositis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Accelerium, S. de R.L. de C.V. - PPDS

    Monterrey, 64000, Mexico

  • Advanced Research Center, Inc.

    Anaheim, California, 92805-5854, United States

  • Aintree University Hospital - NWCRN - PPDS

    Liverpool, Merseyside, L9 7AL, United Kingdom

  • Centro Mineiro de Pesquisa - CMiP

    Juiz de Fora, Minas Gerais, 36010-570, Brazil

  • Hospital Quironsalud Infanta Luisa

    Seville, 41010, Spain

  • LMK Servicos Medicos SS

    Porto Alegre, Rio Grande do Sul, 90480-000, Brazil

  • Revmatologicky ustav

    Prague, Praha, Hlavní Mesto, 128 00, Czechia

  • Unidad de Investigacion de las Enfermedades Reumaticas S.A. De C.V.

    Mexico City, Mexico

  • Western General Hospital Edinburgh - PPDS

    Edinburgh, Midlothian, EH4 2XU, United Kingdom