New drug shows promise for rare muscle disease in small trial

NCT ID NCT05669014

First seen Nov 03, 2025 · Last updated May 14, 2026 · Updated 29 times

Summary

This study tested an investigational drug called daxdilimab in 12 adults with dermatomyositis or anti-synthetase myositis that was not well controlled by standard treatments. The goal was to see if daxdilimab could reduce disease activity and skin symptoms, and help lower steroid use over 24 weeks. Participants received either daxdilimab or a placebo injection, and researchers monitored safety and how the drug moved through the body.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Accelerium, S. de R.L. de C.V. - PPDS

    Monterrey, 64000, Mexico

  • Advanced Research Center, Inc.

    Anaheim, California, 92805-5854, United States

  • Aintree University Hospital - NWCRN - PPDS

    Liverpool, Merseyside, L9 7AL, United Kingdom

  • Centro Mineiro de Pesquisa - CMiP

    Juiz de Fora, Minas Gerais, 36010-570, Brazil

  • Hospital Quironsalud Infanta Luisa

    Seville, 41010, Spain

  • LMK Servicos Medicos SS

    Porto Alegre, Rio Grande do Sul, 90480-000, Brazil

  • Revmatologicky ustav

    Prague, Praha, Hlavní Mesto, 128 00, Czechia

  • Unidad de Investigacion de las Enfermedades Reumaticas S.A. De C.V.

    Mexico City, Mexico

  • Western General Hospital Edinburgh - PPDS

    Edinburgh, Midlothian, EH4 2XU, United Kingdom

Conditions

Explore the condition pages connected to this study.