CYSTIC FIBROSIS
Clinical trials for CYSTIC FIBROSIS explained in plain language.
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CF drug combo trial halted early – did it work?
Disease control TerminatedThis early-stage trial tested whether adding glycerol phenylbutyrate (Ravicti) to standard pancreatic enzyme therapy could improve chloride transport in the nasal cells of adults with cystic fibrosis. Only 16 people enrolled, and the study was terminated before completion. The go…
Matched conditions: CYSTIC FIBROSIS
Phase: PHASE1, PHASE2 • Sponsor: National Jewish Health • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Gene therapy inhaler tested for cystic fibrosis – study halted early
Disease control TerminatedThis study tested a single dose of an inhaled gene therapy (BI 3720931) in adults with cystic fibrosis who cannot use standard CFTR modulator drugs. The goal was to see if it was safe and could improve lung function. The trial was terminated early after enrolling only 5 participa…
Matched conditions: CYSTIC FIBROSIS
Phase: PHASE1, PHASE2 • Sponsor: Boehringer Ingelheim • Aim: Disease control
Last updated May 13, 2026 16:01 UTC
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Experimental CF drug trial halted early – what we know
Disease control TerminatedThis study tested a drug called (R)-Roscovitine in adults with cystic fibrosis who have a specific genetic mutation and a chronic lung infection. The goal was to see if increasing doses of the drug are safe. The trial was planned for 36 participants but was terminated early, so r…
Matched conditions: CYSTIC FIBROSIS
Phase: PHASE2 • Sponsor: University Hospital, Brest • Aim: Disease control
Last updated Apr 28, 2026 13:02 UTC
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Growth hormone trial for CF wasting fails to reach full enrollment
Symptom relief TerminatedThis study aimed to see if growth hormone could help adults with cystic fibrosis who were underweight gain weight and feel better. Only 5 people took part before the study was stopped early. The researchers planned to measure weight, muscle, quality of life, and effects on diabet…
Matched conditions: CYSTIC FIBROSIS
Phase: PHASE1 • Sponsor: University of Massachusetts, Worcester • Aim: Symptom relief
Last updated May 15, 2026 11:55 UTC
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Cystic fibrosis study investigates hidden lung infections
Knowledge-focused TerminatedThis study aimed to find out how many people with cystic fibrosis in France have infections from a type of bacteria called non-tuberculous mycobacteria (NTM). Researchers collected sputum samples and blood tests from 848 patients to compare standard culture methods with a newer b…
Matched conditions: CYSTIC FIBROSIS
Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated May 17, 2026 03:11 UTC
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Cystic fibrosis gene fix shows promise in lab, but study halted
Knowledge-focused TerminatedThis study aimed to see if a special molecule called an oligonucleotide blocker could repair the genetic instructions in cells from people with cystic fibrosis. Researchers collected cells from 16 patients and tested the molecule in the lab. The study was stopped early, so we don…
Matched conditions: CYSTIC FIBROSIS
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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AI listens to lungs: new study aims to detect disease by sound alone
Knowledge-focused TerminatedThis study tested whether artificial intelligence could detect and measure abnormal lung sounds in people with cystic fibrosis, COPD, or pulmonary fibrosis. Researchers used an electronic stethoscope to record breathing sounds during routine checkups and analyzed them with AI. Th…
Matched conditions: CYSTIC FIBROSIS
Sponsor: Groupe Hospitalier de la Region de Mulhouse et Sud Alsace • Aim: Knowledge-focused
Last updated May 11, 2026 20:50 UTC
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Cystic fibrosis study aims to unlock disease secrets
Knowledge-focused TerminatedThis study collected blood, tissue, and other samples from people with cystic fibrosis (CF) and their family members during regular clinic visits. The goal was to build a database for future research into how CF affects the body and how different genes influence the disease. Abou…
Matched conditions: CYSTIC FIBROSIS
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated May 11, 2026 20:49 UTC