CORONARY DISEASE
Clinical trials for CORONARY DISEASE explained in plain language.
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New pacing approach may help more heart failure patients
Disease control CompletedThis study tested two ways to pace the left side of the heart in people with severe heart failure. The standard method uses veins on the heart's surface, while the new method paces from inside the heart chamber. Researchers wanted to see if the inside approach offers more pacing …
Matched conditions: CORONARY DISEASE
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Disease control
Last updated May 17, 2026 11:46 UTC
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Double blood thinner strategy may cut heart risks in Multi-Vessel disease
Disease control CompletedThis study looked at whether taking two blood thinners (clopidogrel and aspirin) for a longer time after getting a heart stent helps prevent future heart attacks, strokes, or death in people with multiple blocked heart arteries. About 8,250 adults aged 18-75 who already had a ste…
Matched conditions: CORONARY DISEASE
Phase: PHASE4 • Sponsor: Harbin Medical University • Aim: Disease control
Last updated May 17, 2026 11:38 UTC
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Heart showdown: stents vs. bypass surgery in major trial
Disease control CompletedThis study compared two ways to treat people with severe blockages in multiple heart arteries: a less invasive procedure using stents guided by a pressure wire (FFR-guided PCI) versus open-heart bypass surgery (CABG). About 1,500 adults with chest pain or signs of heart strain to…
Matched conditions: CORONARY DISEASE
Phase: NA • Sponsor: Stanford University • Aim: Disease control
Last updated May 05, 2026 11:56 UTC
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New balloon shows promise in opening hardened heart blockages
Disease control CompletedThis study tested a tiny balloon catheter designed to open completely blocked heart arteries (chronic total occlusions) before placing a stent. 170 adults with coronary artery disease took part. The main goal was to see if the balloon could be safely delivered, inflated, and remo…
Matched conditions: CORONARY DISEASE
Phase: NA • Sponsor: OrbusNeich • Aim: Disease control
Last updated Apr 23, 2026 12:45 UTC
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Silent heart trouble: does hidden ischemia raise death risk?
Knowledge-focused CompletedThis study looked at whether silent myocardial ischemia (reduced blood flow to the heart without symptoms) increases the risk of heart-related death or problems in people with coronary heart disease. Researchers followed participants for one to three years to track outcomes. The …
Matched conditions: CORONARY DISEASE
Sponsor: University of Rochester • Aim: Knowledge-focused
Last updated May 17, 2026 11:48 UTC
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Gut check: could your microbiome predict heart trouble?
Knowledge-focused CompletedThis study looked at the gut bacteria and bile acids of 80 people—some with coronary artery disease and some healthy. Researchers wanted to see if differences in gut microbes and bile acids might be linked to heart disease. The study was purely observational, meaning no treatment…
Matched conditions: CORONARY DISEASE
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated May 17, 2026 11:34 UTC
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Heart scan radiation under the microscope: global study reveals Real-World doses
Knowledge-focused CompletedThis study measured the amount of radiation people receive during a common heart scan called CCTA. Researchers collected data from 66 adults at multiple hospitals worldwide to see how radiation doses vary and how often dose-saving techniques are used. The goal was to help make th…
Matched conditions: CORONARY DISEASE
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated May 13, 2026 16:08 UTC