COMMUNITY-ACQUIRED PNEUMONIA
Clinical trials for COMMUNITY-ACQUIRED PNEUMONIA explained in plain language.
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New drug shows promise for severe pneumonia patients in ICU
Disease control CompletedThis study tested an experimental drug called AON-D21 in 150 ICU patients with severe community-acquired pneumonia. The goal was to see if adding AON-D21 to standard care is safe and helps patients recover faster compared to a placebo. The trial is now complete, and results will …
Matched conditions: COMMUNITY-ACQUIRED PNEUMONIA
Phase: PHASE2 • Sponsor: Aptarion Biotech AG • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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Could a simple steroid save lives in severe pneumonia?
Disease control CompletedThis study tested whether adding low-dose hydrocortisone (a steroid) to standard care could help more people survive severe community-acquired pneumonia. About 950 adults in intensive care took part. The goal was to see if the steroid reduced deaths within 28 days.
Matched conditions: COMMUNITY-ACQUIRED PNEUMONIA
Phase: PHASE3 • Sponsor: University Hospital, Tours • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Swab alert slashes unnecessary antibiotic use in ICU pneumonia patients
Disease control CompletedThis study tested whether telling doctors the results of a rapid nose swab test could reduce the use of a strong antibiotic called vancomycin in adults with pneumonia in the intensive care unit. The trial involved 277 participants and compared usual care to getting a pager alert …
Matched conditions: COMMUNITY-ACQUIRED PNEUMONIA
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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ER CT scans could slash pneumonia misdiagnosis
Diagnosis CompletedThis study looked at whether using a chest CT scan, in addition to standard tests, helps emergency doctors more accurately diagnose community-acquired pneumonia in adults. Researchers studied 339 patients with suspected pneumonia to see how often the CT scan changed the initial d…
Matched conditions: COMMUNITY-ACQUIRED PNEUMONIA
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Diagnosis
Last updated May 04, 2026 16:24 UTC
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Which breathing aid is best for sick kids? new study compares two common methods
Symptom relief CompletedThis study looked at 80 children aged 1 month to 5 years with severe breathing problems from pneumonia or bronchiolitis. It compared two types of breathing support: High-Velocity Nasal Insufflation (HVNI) and nasal Continuous Positive Airway Pressure (nCPAP). The goal was to see …
Matched conditions: COMMUNITY-ACQUIRED PNEUMONIA
Phase: NA • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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Smart reports help doctors use antibiotics wisely
Knowledge-focused CompletedThis study tested whether automated electronic reports could help doctors prescribe antibiotics more appropriately for common infections like pneumonia, ear infections, and sore throat. Over 26,000 patients were included, and the reports compared prescribing patterns before and a…
Matched conditions: COMMUNITY-ACQUIRED PNEUMONIA
Phase: NA • Sponsor: Children's Hospital of Philadelphia • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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Antibiotic penetration in chest infections measured
Knowledge-focused CompletedThis study looked at how the antibiotics amoxicillin and clavulanic acid get into the fluid around the lungs in people with serious chest infections. Eleven adults who needed a chest tube took part. The goal was to understand how much antibiotic reaches the infected area, which c…
Matched conditions: COMMUNITY-ACQUIRED PNEUMONIA
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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New score could help doctors spot Drug-Resistant pneumonia faster
Knowledge-focused CompletedThis study created and tested a simple scoring system called RESPIRE to help doctors quickly identify pneumonia caused by drug-resistant bacteria. Researchers looked at data from 300 adults who came to the emergency room with pneumonia. The goal is to help doctors choose the righ…
Matched conditions: COMMUNITY-ACQUIRED PNEUMONIA
Sponsor: Azienda Ospedaliero-Universitaria Careggi • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC