COLORECTAL CANCER METASTATIC
Clinical trials for COLORECTAL CANCER METASTATIC explained in plain language.
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Chemo holidays put to the test: can scheduled breaks beat continuous treatment for advanced colorectal cancer?
Disease control Not yet recruitingThis phase 3 trial tests whether giving the targeted therapy cetuximab plus FOLFIRI chemotherapy in scheduled breaks works as well as continuous treatment for people with a specific genetic type of metastatic colorectal cancer (RAS/BRAF wild-type). The study compares how long the…
Matched conditions: COLORECTAL CANCER METASTATIC
Phase: PHASE3 • Sponsor: Charite University, Berlin, Germany • Aim: Disease control
Last updated Jul 31, 2026 00:00 UTC
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Can two immune boosters outsmart Chemo-Resistant colon cancer?
Disease control Not yet recruitingThis phase 3 trial is testing whether adding two immune-boosting drugs, iparomlimab and tuvonralimab, to standard chemotherapy can help people with a specific type of metastatic colorectal cancer that has stopped responding to first-line treatment. The study includes about 270 ad…
Matched conditions: COLORECTAL CANCER METASTATIC
Phase: PHASE3 • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated Jul 29, 2026 00:00 UTC
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Experimental drug SHR-A1904 takes on Hard-to-Treat colorectal cancer
Disease control Not yet recruitingThis phase 2 trial tests an experimental drug called SHR-A1904 in people with advanced colorectal cancer that has spread and no longer responds to standard treatments. The study aims to see if the drug is safe and can shrink tumors or slow the disease. Participants must have alre…
Matched conditions: COLORECTAL CANCER METASTATIC
Phase: PHASE2 • Sponsor: Peking University Cancer Hospital & Institute • Aim: Disease control
Last updated Jul 16, 2026 00:00 UTC
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New drug cocktail hopes to tackle advanced colon cancer
Disease control Not yet recruitingThis study tests a new drug called HDM2017 combined with standard treatment (fruquintinib) in 120 people with advanced colorectal cancer that has spread. The goal is to find the safest dose and see if the combination can shrink tumors. Participants must have tried other treatment…
Matched conditions: COLORECTAL CANCER METASTATIC
Phase: PHASE1, PHASE2 • Sponsor: Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Poop pills plus chemo: new hope for stubborn colon cancer?
Disease control Not yet recruitingThis early-phase trial tests whether transplanting gut bacteria from young donors (via capsules or a tube) can help immunotherapy work better in people with a type of advanced colorectal cancer that usually doesn't respond to immunotherapy. Ten patients who have already tried sta…
Matched conditions: COLORECTAL CANCER METASTATIC
Phase: EARLY_PHASE1 • Sponsor: The First Affiliated Hospital of Xiamen University • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Could a constipation drug help keep colorectal cancer at bay?
Disease control Not yet recruitingThis phase II trial is testing whether adding lubiprostone, a drug usually used for constipation, to standard maintenance therapy can delay cancer recurrence in adults with colorectal cancer that has spread to the lining of the abdomen. About 124 participants who have had surgery…
Matched conditions: COLORECTAL CANCER METASTATIC
Phase: PHASE2 • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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New virus combo tackles liver metastases in colorectal cancer
Disease control Not yet recruitingThis early-stage trial tests a new approach for people with colorectal cancer that has spread to the liver and hasn't responded to standard treatments. It combines a virus designed to attack cancer cells (BioTTT001) with two drugs (toripalimab and regorafenib). The study will enr…
Matched conditions: COLORECTAL CANCER METASTATIC
Phase: PHASE1 • Sponsor: China Medical University, China • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC