COLORECTAL ADENOMA

This study is testing whether a 7-day course of the drug linaclotide can produce biological changes in colon polyps or early-stage colorectal tumors. About 230 patients scheduled for a colonoscopy or surgery will take either linaclotide or a placebo pill daily for one week before…

This study aims to see how well a new at-home stool test, called LifeKit Prevent, can detect colon cancer and precancerous growths (polyps). Researchers will enroll 12,000 adults aged 40+ who are already scheduled for a screening colonoscopy. Participants will use the new test an…

This study is testing a new computer program designed to help doctors during colonoscopies. The software analyzes images from the procedure to automatically find growths and tell doctors how likely they are to be pre-cancerous (adenoma) or non-cancerous (non-adenoma). Researchers…

This study is testing an experimental vaccine designed to teach the body's immune system to attack and kill colon polyp cells. It aims to prevent these polyps, which can turn into colorectal cancer, from growing back after removal. About 110 people who recently had a large or hig…

This study is testing whether taking aspirin daily or in on-and-off cycles can help prevent colorectal cancer in people who have precancerous growths called adenomas. Researchers are comparing three groups: daily aspirin, intermittent aspirin, and placebo, to see which schedule b…