COCAINE USE DISORDER

This study tests whether a smartphone app can help people who are already on methadone treatment reduce their use of opioids and cocaine. About 240 adults who use both opioids and cocaine will either receive standard methadone care or also get the app, which randomly asks for rem…

This study looks at whether using a smartphone app that gives rewards for drug-free saliva tests works for older adults with opioid, cocaine, or methamphetamine use disorder. About 175 people aged 18 and older will use the app and provide test samples. The goal is to see if age a…

This study aimed to see if exenatide, a drug approved for diabetes, could reduce the urge to use cocaine. Researchers planned to give the drug or a placebo to adults with long-term cocaine use and measure how much cocaine they chose to take. However, the study was withdrawn befor…

This study looks at whether a single 25 mg dose of psilocybin (the active ingredient in magic mushrooms) can be safely given to people with cocaine use disorder who want to quit. Ten adults from Los Angeles will take the drug in a comfortable room with two clinicians present, and…

This study is testing a digital program called LDART to see if it helps adults who use stimulants like cocaine or methamphetamine. Researchers want to know if people find it easy to use and if it helps reduce how often they use these drugs. The study involves 80 participants in C…

This study looks at whether a single dose of methylphenidate (a mild stimulant) can help people with cocaine use disorder weaken their drug-related memories. About 51 adults will have brain scans and skin response tests while recalling drug cues after taking either the medication…