CHRONIC RHINOSINUSITIS
Clinical trials for CHRONIC RHINOSINUSITIS explained in plain language.
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Can a simple antiseptic rinse improve sinus surgery recovery?
Disease control CompletedThis study looked at whether rinsing the nose with diluted povidone-iodine (a common antiseptic) after sinus surgery helps people with chronic sinusitis recover better than standard saline or mucomyst rinses. Forty-eight adults who had sinus surgery used one of the three rinses d…
Matched conditions: CHRONIC RHINOSINUSITIS
Phase: NA • Sponsor: Pusan National University Hospital • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Melatonin may calm nerves before sinus surgery – study finds optimal dose
Symptom relief CompletedThis study tested different doses of melatonin (3, 5, and 10 mg) compared to a placebo in 160 adults undergoing sinus surgery. The goal was to see which dose best reduces anxiety and pain while keeping heart rate and blood pressure stable. Results could help doctors choose the ri…
Matched conditions: CHRONIC RHINOSINUSITIS
Phase: PHASE4 • Sponsor: Aswan University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Sinus surgery showdown: crushing vs cutting for a common nose problem
Symptom relief CompletedThis study looked at two methods to treat concha bullosa, a condition where the middle turbinate in the nose is enlarged and can block sinuses. 62 adults with chronic sinusitis were randomly assigned to have the turbinate crushed or partially removed during sinus surgery. After o…
Matched conditions: CHRONIC RHINOSINUSITIS
Phase: NA • Sponsor: Helsinki University Central Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Nose injection may ease pain after sinus surgery
Symptom relief CompletedThis study tested whether injecting the numbing drug ropivacaine into the nose can reduce pain after endoscopic sinus surgery. 184 adults having sinus surgery were randomly given either ropivacaine or a saltwater placebo injection. The main goal was to measure pain intensity and …
Matched conditions: CHRONIC RHINOSINUSITIS
Phase: PHASE3 • Sponsor: University Hospital, Lille • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Sedative drug may improve visibility in sinus surgery
Symptom relief CompletedThis study tested whether adding the sedative drug dexmedetomidine to anesthesia improves the view for surgeons during endoscopic sinus surgery. Fifty adults with rhinosinusitis were enrolled. The goal was to see if the drug could make the surgical field clearer, potentially maki…
Matched conditions: CHRONIC RHINOSINUSITIS
Phase: PHASE4 • Sponsor: Menoufia University • Aim: Symptom relief
Last updated Jun 26, 2026 14:27 UTC
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French version of child sinusitis questionnaire under review
Knowledge-focused CompletedThis study tested whether a French translation of the SN-5 questionnaire, which measures quality of life in children with chronic rhinosinusitis, works as well as the original English version. Researchers asked 89 children (ages 2–12) and their parents to fill out the questionnai…
Matched conditions: CHRONIC RHINOSINUSITIS
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Sinus trouble linked to brain fog: new study reveals sleep and fatigue as key factors
Knowledge-focused CompletedThis study looked at 134 adults with chronic sinusitis to see if sleep problems and daytime tiredness predict declines in thinking skills and daily functioning. Participants filled out questionnaires about their symptoms and quality of life. The goal was to better understand how …
Matched conditions: CHRONIC RHINOSINUSITIS
Sponsor: Sinai University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC