CHRONIC MYELOGENOUS LEUKEMIA

This study is for people with chronic myeloid leukemia who are already taking the drug asciminib and benefiting from it. The goal is to monitor long-term safety and side effects while they continue treatment. About 347 participants will be followed, and doctors will also check if…

This study compares two approaches to prevent graft-versus-host disease (GVHD), a serious complication where donor cells attack the patient's body after a stem cell transplant. About 400 adults with blood cancers like leukemia or lymphoma will receive either thymoglobulin or a co…

This study uses a cord blood transplant after strong chemotherapy and radiation to treat various blood cancers like leukemia and lymphoma. About 200 participants will receive the transplant to see if it improves survival one year later. The approach aims to replace diseased bone …

This study tests a drug called asciminib in children aged 1 to 18 with a specific leukemia (Ph+ CML-CP). The goal is to see if the drug can lower the number of cancer cells in the blood. About 50 children will take the drug, either newly diagnosed or if other treatments stopped w…

This study reviews the medical charts of up to 3,000 people with chronic myeloid leukemia (CML) who received standard tyrosine kinase inhibitor drugs (like imatinib) outside of a clinical trial at MD Anderson Cancer Center. The goal is to learn how these patients respond to treat…

This study gathers basic survival and complication information from 2000 people receiving stem cell transplants for blood cancers or immune diseases. The goal is to build a database for future research and to improve patient care. No new treatments are being tested; only standard…

This study looks at how the body processes venetoclax when the tablet is crushed and mixed into a liquid for children and young adults with blood cancers like leukemia or lymphoma. About 30 participants who already take venetoclax this way will have their blood levels measured. T…