CHRONIC GRANULOMATOUS DISEASE
Clinical trials for CHRONIC GRANULOMATOUS DISEASE explained in plain language.
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Partial match, full hope: new transplant approach aims to cure rare immune disease
⭐️ CURE ⭐️ OngoingThis early-phase study tests whether a bone marrow transplant from a partially matched relative can safely cure chronic granulomatous disease (CGD), a condition causing severe infections and inflammation. Up to 4 participants aged 4-65 will receive chemotherapy, radiation, and im…
Matched conditions: CHRONIC GRANULOMATOUS DISEASE
Phase: EARLY_PHASE1 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: ⭐️ CURE ⭐️
Last updated May 07, 2026 18:42 UTC
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New hope for kids with 'Bubble Boy' disease: stem cell transplant study
Disease control OngoingThis study tests a stem cell transplant (bone marrow transplant) for people with severe immune system problems, like SCID (bubble boy disease) and Wiskott-Aldrich syndrome. The goal is to replace the faulty immune system with healthy donor cells. 57 participants will be followed …
Matched conditions: CHRONIC GRANULOMATOUS DISEASE
Phase: NA • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated May 17, 2026 04:36 UTC
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New gene therapy could help people with rare immune disorder fight infections
Disease control ENROLLING_BY_INVITATIONThis study tests a new gene therapy for people with chronic granulomatous disease (CGD), a genetic disorder that makes them prone to severe infections. The treatment takes the patient's own stem cells, adds a missing gene in the lab, and puts them back into the body. The goal is …
Matched conditions: CHRONIC GRANULOMATOUS DISEASE
Phase: PHASE1, PHASE2 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated May 17, 2026 04:31 UTC
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Gene editing breakthrough offers hope for rare immune disease
Disease control ENROLLING_BY_INVITATIONThis study tests a new gene therapy for people with chronic granulomatous disease (CGD), a rare immune disorder that causes severe infections. The treatment uses the patient's own blood stem cells, which are modified in a lab with a precise gene-editing tool called prime editing,…
Matched conditions: CHRONIC GRANULOMATOUS DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Prime Medicine, Inc. • Aim: Disease control
Last updated May 17, 2026 04:17 UTC
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Milder stem cell transplant offers hope for kids with rare immune diseases
Disease control OngoingThis study tests a stem cell transplant for children and young adults up to age 28 with serious immune system disorders. The goal is to replace their faulty immune cells with healthy donor cells using a milder chemotherapy-like preparation to reduce side effects. The study tracks…
Matched conditions: CHRONIC GRANULOMATOUS DISEASE
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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Gene therapy trial for rare immune disease pulled before starting
Disease control TerminatedThis study aimed to test a gene therapy for X-linked chronic granulomatous disease, a rare immune disorder that makes patients prone to severe infections. The plan was to take the patient's own blood stem cells, add a corrected gene, and return them to the body. However, the tria…
Matched conditions: CHRONIC GRANULOMATOUS DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Helixmith Co., Ltd. • Aim: Disease control
Last updated May 12, 2026 13:43 UTC