CHONDROSARCOMA

This study tests whether proton beam therapy, sometimes combined with standard radiation, can control skull base chondrosarcoma—a rare tumor near the brain. Fifteen adults who had surgery to remove as much tumor as possible will receive this targeted radiation. The main goal is t…

This early-phase study tests an oral drug called LY3410738 in people with advanced solid tumors (like bile duct cancer, bone cancer, or brain tumors) that have certain IDH gene mutations. The main goals are to find the safest dose and see if the drug can shrink tumors or slow the…

This early-phase trial tests whether zoledronic acid, a drug usually used for bone thinning, can help shrink or control chondrosarcoma tumors before surgery. About 17 adults with this rare bone cancer will receive the drug and then have their tumors removed. The main goals are to…

This study tests a drug called AG-120 in people with a rare bone cancer (chondrosarcoma) that has a specific genetic change (IDH1 mutation). The goal is to see if the drug can stop or slow the cancer from growing. The study includes 6 adults with advanced or recurrent disease who…

This study looks back at 77 cases of a rare bone tumor called clear cell chondrosarcoma in Italy. Researchers want to learn more about how the tumor behaves and what affects a patient's outlook. By reviewing medical records and scans from 1982 to 2023, they hope to create a model…