CASTRATION-RESISTANT PROSTATE CANCER
Clinical trials for CASTRATION-RESISTANT PROSTATE CANCER explained in plain language.
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New drug combo tested for Tough-to-Treat prostate cancer
Disease control CompletedThis study tested a combination of two drugs, talazoparib and temozolomide, for men with advanced prostate cancer that had spread and stopped responding to standard hormone therapies. The first part of the study aimed to find the safest dose, and the second part tested how well t…
Matched conditions: CASTRATION-RESISTANT PROSTATE CANCER
Phase: PHASE1, PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Skin patch testosterone tested as new weapon against tough prostate cancer
Disease control CompletedThis early-stage study tested a new approach for men with advanced prostate cancer that has stopped responding to standard hormone-blocking therapy. Researchers wanted to see if it was practical and safe to give testosterone through a skin patch, alternating with a cancer drug ca…
Matched conditions: CASTRATION-RESISTANT PROSTATE CANCER
Phase: EARLY_PHASE1 • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Radioactive drug trial offers new hope for men with Tough-to-Treat prostate cancer
Disease control CompletedThis study tested whether adding a radioactive drug (I-131-1095) to standard medication (enzalutamide) could better control advanced prostate cancer that had worsened on a prior drug (abiraterone). It involved 120 men whose cancer had spread and was visible on a special PSMA scan…
Matched conditions: CASTRATION-RESISTANT PROSTATE CANCER
Phase: PHASE2 • Sponsor: Progenics Pharmaceuticals, Inc. • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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New injection aims to hold off chemotherapy for older men with tough prostate cancer
Disease control CompletedThis study tested whether a steroid drug called triamcinolone, given as a monthly muscle injection alongside standard hormone therapy, could help control advanced prostate cancer that had stopped responding to initial treatments. It involved 55 men, mostly over 70, with the goal …
Matched conditions: CASTRATION-RESISTANT PROSTATE CANCER
Phase: PHASE2 • Sponsor: Barts & The London NHS Trust • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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New hope for tough prostate cancers: old drug targets genetic weakness
Disease control CompletedThis study tested whether the chemotherapy drug carboplatin could help control advanced prostate cancer that had spread and stopped responding to standard hormone treatments. It focused on a small group of 16 men whose tumors had specific genetic changes that might make them more…
Matched conditions: CASTRATION-RESISTANT PROSTATE CANCER
Phase: PHASE2 • Sponsor: Centre Francois Baclesse • Aim: Disease control
Last updated Mar 18, 2026 18:25 UTC
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New pill offers hope for men with Tough-to-Treat prostate cancer
Disease control CompletedThis study tested a new approach for men whose prostate cancer has spread and stopped responding to standard hormone-blocking treatments. Researchers gave participants a high-dose oral testosterone pill in a one-week-on, one-week-off cycle for three months to see if it could shri…
Matched conditions: CASTRATION-RESISTANT PROSTATE CANCER
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins • Aim: Disease control
Last updated Mar 09, 2026 14:25 UTC