CASTRATION-RESISTANT PROSTATE CANCER
Clinical trials for CASTRATION-RESISTANT PROSTATE CANCER explained in plain language.
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DNA vaccine combo shows promise against tough prostate cancer
Disease control OngoingThis study tests whether adding a second DNA vaccine to a standard immunotherapy (pembrolizumab) can help men with advanced prostate cancer that no longer responds to hormone therapy. About 60 participants will receive either one or two DNA vaccines plus pembrolizumab for up to t…
Matched conditions: CASTRATION-RESISTANT PROSTATE CANCER
Phase: PHASE2 • Sponsor: University of Wisconsin, Madison • Aim: Disease control
Last updated May 17, 2026 01:00 UTC
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Bone drug breakthrough: could less be more for cancer patients?
Disease control OngoingThis study looks at whether people with breast or prostate cancer that has spread to the bones can safely stop or reduce their bone-strengthening medication after taking it for at least two years. The goal is to see if this approach maintains quality of life and prevents bone com…
Matched conditions: CASTRATION-RESISTANT PROSTATE CANCER
Phase: PHASE4 • Sponsor: Ottawa Hospital Research Institute • Aim: Disease control
Last updated May 11, 2026 20:52 UTC
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Experimental cell therapy targets Hard-to-Treat prostate cancer
Disease control OngoingThis early-phase trial tests a new type of immune cell therapy (PSMA-UCAR T cells) in 3 men with advanced prostate cancer that no longer responds to standard treatments. The main goal is to check safety and find the right dose, not to cure the disease. Participants must have meta…
Matched conditions: CASTRATION-RESISTANT PROSTATE CANCER
Phase: PHASE1 • Sponsor: Shanghai Changzheng Hospital • Aim: Disease control
Last updated May 11, 2026 20:39 UTC
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Engineered immune cells take on Hard-to-Treat prostate cancer
Disease control OngoingThis early-phase trial tests a new treatment for men with advanced prostate cancer that has stopped responding to standard therapies. The treatment uses the patient's own immune cells, which are modified in a lab to better recognize and attack cancer cells. Up to 18 participants …
Matched conditions: CASTRATION-RESISTANT PROSTATE CANCER
Phase: EARLY_PHASE1 • Sponsor: Shanghai Changzheng Hospital • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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New imaging agent aims to spot Hard-to-Find cancers
Diagnosis TerminatedThis study was designed to test a new imaging agent called 111In-ABD147 that targets a protein (DLL3) found on many solid tumors, including prostate cancer and neuroendocrine tumors. The goal was to see if SPECT scans using this agent could better detect cancer that has spread. T…
Matched conditions: CASTRATION-RESISTANT PROSTATE CANCER
Phase: EARLY_PHASE1 • Sponsor: Thomas Hope • Aim: Diagnosis
Last updated May 17, 2026 00:50 UTC